Gene Symbol | SNTG2 |
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Entrez Gene | 54221 |
Alt Symbol | G2SYN, SYN5 |
Species | Human |
Gene Type | protein-coding |
Description | syntrophin, gamma 2 |
Other Description | gamma-2-syntrophin|syntrophin-5 |
Swissprots | Q05AH5 Q9NY99 |
Accessions | EAX01092 Q9NY99 AJ003029 CAB92969 BC035783 BC125251 AAI25252 BG208326 XM_011510364 XP_011508666 XM_011510365 XP_011508667 XM_011510366 XP_011508668 XM_011510367 XP_011508669 XM_011510368 XP_011508670 NM_018968 NP_061841 |
Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane. |
Tissue Specificity | Widely expressed. Strong expression in brain and testis. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia. {ECO:0000269|PubMed:10747910}. |
γ2-Syntrophin CRISPR/Cas9 KO Plasmid (h) - sc-409960 from Santa Cruz Biotechnology
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γ2-Syntrophin HDR Plasmid (h) - sc-409960-HDR from Santa Cruz Biotechnology
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γ2-Syntrophin Double Nickase Plasmid (h) - sc-409960-NIC from Santa Cruz Biotechnology
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γ2-Syntrophin Double Nickase Plasmid (h2) - sc-409960-NIC-2 from Santa Cruz Biotechnology
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γ2-Syntrophin CRISPR Activation Plasmid (h) - sc-409960-ACT from Santa Cruz Biotechnology
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γ2-Syntrophin CRISPR Activation Plasmid (h2) - sc-409960-ACT-2 from Santa Cruz Biotechnology
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γ2-Syntrophin Lentiviral Activation Particles (h) - sc-409960-LAC from Santa Cruz Biotechnology
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γ2-Syntrophin Lentiviral Activation Particles (h2) - sc-409960-LAC-2 from Santa Cruz Biotechnology
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γ2-syntrophin siRNA (h) - sc-43443 from Santa Cruz Biotechnology
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γ2-syntrophin shRNA Plasmid (h) - sc-43443-SH from Santa Cruz Biotechnology
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γ2-syntrophin shRNA (h) Lentiviral Particles - sc-43443-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN20282 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20282 from Sigma-Aldrich
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SNTG2 siRNA (Human) - CRJ0035 from Cohesion Biosciences
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SNTG2 - MBS8203044 from MyBioSource
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shRNA set against Human SNTG2 (NM_018968.3) - SHH414492 from Creative biogene
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SNTG2 shRNA Plasmid (Human) - CHJ0035 from Cohesion Biosciences
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SNTG2 miRNA 3'UTR clone - MiUTR4H-TG08379 from Creative biogene
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