Nampt

Gene Symbol	Nampt
Entrez Gene	297508
Alt Symbol	Pbef, Pbef1
Species	Rat
Gene Type	protein-coding
Description	nicotinamide phosphoribosyltransferase
Other Description	NAmPRTase|pre-B-cell colony enhancing factor 1|pre-B-cell colony-enhancing factor 1 homolog|visfatin
Swissprots	Q2VT47 Q80Z29
Accessions	EDM03273 Q80Z29 AB081730 BAC66022 AY831728 AAX49410 BC085681 AAH85681 NM_177928 NP_808789
Function	Catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. {ECO:0000250|UniProtKB:P43490, ECO:0000250|UniProtKB:Q99KQ4}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12782293}. Cytoplasm {ECO:0000269|PubMed:12782293}. Secreted {ECO:0000250|UniProtKB:P43490}. Note=Under non-inflammatory conditions, visfatin predominantly exhibits a granular pattern within the nucleus. Secreted by endothelial cells upon IL-1beta stimulation. Abundantly secreted in milk, reaching 100-fold higher concentrations compared to maternal serum. {ECO:0000250|UniProtKB:P43490}.
Tissue Specificity	Expressed in various tissues. At the highest level in liver and at the second highest in heart. The amount is higher in heart than in lung. {ECO:0000269|PubMed:12782293}.
Top Pathways	Nicotinate and nicotinamide metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Nicotinamide phosphoribosyltransferase (NAMPT), Rat, ELISA Kit - E02N0539 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Nicotinamide phosphoribosyltransferase, Nampt, Rat, ELISA Kit - E0638r from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Visfatin (VF), Rat, ELISA Kit - SEA638Ra from ARP American Research Products Category ELISA Kit Prices $704.00 Sizes 96 t Sensitivity 0.55ng/mL Range 1.56-100ng/mL

Visfatin, Rat, ELISA Kit - CSB-E08941r from ARP American Research Products Category ELISA Kit Prices $586.00, $856.00, $858.00, $860.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.78 ng/ml Range 3.12 ng/ml-200 ng/ml

Visfatin, Rat, ELISA Kit - E02V0003 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 25-500ng/ml

Visfatin, Rat, ELISA Kit - YHB1138Ra from ARP American Research Products Category ELISA Kit

Rat Visfatin ELISA Kit - RV0046 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Visfatin, ELISA Kit - MBS721527 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

visfatin, ELISA Kit - MBS729774 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Visfatin, ELISA Kit - MBS014074 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Visfatin (VF), ELISA Kit - MBS2021243 from MyBioSource Category ELISA Kit Prices $370.00, $550.00, $750.00, $3,065.00, $5,550.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.62ng/mL. Range 1.56-100ng/mL

Visfatin (VF), ELISA Kit - MBS269269 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

nicotinamide phosphoribosyltransferase, ELISA Kit - MBS700290 from MyBioSource Category ELISA Kit Prices $250.00, $590.00, $855.00, $3,110.00, $5,890.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.78 ng/ml Range 3.12 ng/ml-200 ng/ml

Rat visfatin ELISA Kit - CSB-E08941r from Cusabio Category ELISA Kit Sensitivity 0.78 ng/ml Range 3.12 ng/ml-200 ng/ml

Rat Visfatin ELISA - E02V0003 from BlueGene Biotech Category ELISA Kit Sensitivity 1.0 ng/mL

ELISA Kit for Visfatin (VF) - SEA638Ra from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.62ng/mL. Range 1.563-100ng/mL The standard curve concentrations used for the ELISA's were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL

Visfatin - ABE-121-02 from Nordic BioSite Sensitivity 0.6 ng/mL

Rat Visfatin (VF) ELISA Kit - EKU08156 from Biomatik Category ELISA Kit Prices $718.00, $3,196.00, $5,817.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.58 ng/mL Range 1.56-100 ng/mL

Rat VF(Visfatin) ELISA Kit - E-EL-R1067 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mL Range 0.16~10 ng/mL

Rat Visfatin ELISA Kit - abx156229 from Abbexa Category ELISA Kit Range 1.56 ng/ml - 100 ng/ml

Rat Visfatin ELISA Kit - abx256095 from Abbexa Category ELISA Kit Sensitivity 0.094 ng/ml Range 0.156 ng/ml - 10 ng/ml

Rat Visfatin ELISA Kit - abx051489 from Abbexa Category ELISA Kit Sensitivity 0.05 ng/ml Range 0.3 ng/ml - 20 ng/ml

Visfatin (VF), Rat, ELISA Kit - DL-VF-Ra from ARP American Research Products Category ELISA Kit Prices $715.00 Sizes 96 t Range 0.156-10 ng/mL

Rat visfatin ELISA Kit - EKC39876 from Biomatik Category ELISA Kit Prices $861.00, $3,228.75, $6,027.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.78 ng/ml Range 3.12 ng/ml-200 ng/ml

Rat Nicotinamide phosphoribosyltransferase ELISA Kit - EKE51798 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Range 78-5000 pg/ml

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