DGKQ

Gene Symbol DGKQ
Entrez Gene 1609
Alt Symbol DAGK, DAGK4, DAGK7
Species Human
Gene Type protein-coding
Description diacylglycerol kinase, theta 110kDa
Other Description DAG kinase theta|DGK-theta|diacylglycerol kinase theta|diglyceride kinase theta
Swissprots Q6P3W4 P52824
Accessions EAW82630 EAW82631 EAW82632 P52824 AB209503 BAD92740 AW139889 BC063801 AAH63801 DN990411 DQ596864 GU727647 ADU87648 L38707 AAA98749 XM_011513411 XP_011511713 XM_011513412 XP_011511714 XM_011513413 XP_011511715 XM_011513414 XP_011511716 XM_011513415 XP_011511717 NM_001347 NP_001338
Function Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor (By similarity). May be involved in cAMP- induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity. {ECO:0000250, ECO:0000269|PubMed:17664281}.
Subcellular Location Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton. Nucleus. Nucleus speckle. Note=Translocates to the nucleus in response to thrombin stimulation (By similarity). Translocates to the plasma membrane in response to steroid hormone receptor stimulation. Translocation to the plasma membrane is dependent on G-protein coupled receptor stimulation and subsequent activation of PRKCE and probably PRKCH. {ECO:0000250}.
Top Pathways Choline metabolism in cancer, Glycerolipid metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system

DGK-θ (H-130) - sc-66861 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DGK-θ (H-130): sc-66861. Western blot analysis of DGK-θ expression in non-transfected: sc-117752 (A) and human DGK-θ transfected: sc-117226 (B) 293T whole cell lysates.

DGK-θ (E-5) - sc-137197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DGK-θ (E-5): sc-137197. Western blot analysis of DGK-θ expression in non-transfected: sc-117752 (A) and human DGK-θ transfected: sc-117226 (B) 293T whole cell lysates.

DGK-θ (K-13) - sc-46577 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DGK-θ (24) - sc-135882 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
DGK-θ (24): sc-135882. Western blot analysis of DGK-θ expression in rat brain tissue extract.

Anti-DAGK antibody - ab80203 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DAGK antibody (ab80203) at 1/500 dilutionLane 1 : extracts from HT-29 cellsLane 2 : extracts from HT-29 cells with immunizing peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-DAGK antibody - ab140437 from Abcam

Prices $242.00
Sizes 200 µl
Host Goat
Clonality Polyclonal

Anti-DGKQ Antibody (aa691-740) - LS-C118937 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HT-29 cells, using DGKQ Antibody. The lane on the right is treated with the synthesized peptide.

Anti-DGKQ Antibody (N-Terminus, AP) - LS-C225116 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (N-Terminus, APC) - LS-C225117 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (N-Terminus, FITC) - LS-C225120 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (N-Terminus, Biotin) - LS-C225119 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (N-Terminus, Azide-free, HRP) - LS-C225121 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (C-Terminus, AP) - LS-C225122 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (C-Terminus, APC) - LS-C225123 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (N-Terminus, PE) - LS-C225124 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (aa751-800) - LS-C135259 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DGKQ antibody LS-C135259 Western blot of ACHN lysate.

Anti-DGKQ Antibody (C-Terminus, Biotin) - LS-C225125 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (C-Terminus, Azide-free, HRP) - LS-C225127 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (C-Terminus, FITC) - LS-C225126 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (Ser725) - LS-C177020 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of DGK- (S725) pAb in paraffin-embedded human brain tissue.

Anti-DGKQ Antibody (C-Terminus, PE) - LS-C225128 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (C-Terminus, Azide-free) - LS-C327194 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (C-Terminus, Azide-free) - LS-C327192 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DGKQ Antibody (aa295-298) IHC-plus™ - LS-B10348 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-DGKQ antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10348 concentration 5 ug/ml.

DGK-theta Antibody (652308) - MAB6598 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 652308
Western Blot DGK-theta Antibody (652308)
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