EIF3M

Gene Symbol EIF3M
Entrez Gene 10480
Alt Symbol B5, GA17, PCID1, TANGO7, hfl-B5
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 3, subunit M
Other Description B5 receptor|PCI domain containing 1 (herpesvirus entry mediator)|PCI domain-containing protein 1|dendritic cell protein|eukaryotic translation initiation factor 3 subunit M|fetal lung protein B5|transport and golgi organization 7 homolog
Swissprots Q9BXW1 Q53HL6 A8K7X4 Q2F836 B4E2Q4 Q7L2H7 O60735
Accessions EAW68217 EAW68218 Q7L2H7 AF064603 AAC17108 AF277183 AAK07542 AK001768 AK131064 AK222564 BAD96284 AK292139 BAF84828 AK300002 BAG61821 AK304378 BAG65216 AK307121 AK312512 BAG35413 AV713889 AY769947 AAX12524 BC011937 BC019103 AAH19103 BC020458 BC051292 AAH51292 BE935691 CK002866 CR450300 CAG29296 DB479224 DQ185042 ABD14422 XM_011519840 XP_011518142 XM_011519841 XP_011518143 NM_001307929 NP_001294858 NM_006360 NP_006351
Function Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2). {ECO:0000255|HAMAP-Rule:MF_03012, ECO:0000269|PubMed:15919898, ECO:0000269|PubMed:17403899}.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03012}.
Tissue Specificity Broadly expressed. {ECO:0000269|PubMed:15919898}.

EIF3M-Over-expression-Lysate - LY12028a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag EIF3M (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EIF3M gene

EIF3M overexpression lysate - LY416700 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

EIF3M 293 Cell Lysate - 407798 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

EIF3M Overexpression Lysate (Native) - NBL1-10200 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: EIF3M Overexpression Lysate (Adult Normal) [NBL1-10200] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for EIF3M.

EIF3M Over-expression Lysate Product - GWB-62083A from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human EIF3M Knockdown Stable Cell Line - CSC-DC004823 from Creative biogene

Category Cell Line
Species Human
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