EIF3M

Gene Symbol EIF3M
Entrez Gene 10480
Alt Symbol B5, GA17, PCID1, TANGO7, hfl-B5
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 3, subunit M
Other Description B5 receptor|PCI domain containing 1 (herpesvirus entry mediator)|PCI domain-containing protein 1|dendritic cell protein|eukaryotic translation initiation factor 3 subunit M|fetal lung protein B5|transport and golgi organization 7 homolog
Swissprots Q9BXW1 Q53HL6 A8K7X4 Q2F836 B4E2Q4 Q7L2H7 O60735
Accessions EAW68217 EAW68218 Q7L2H7 AF064603 AAC17108 AF277183 AAK07542 AK001768 AK131064 AK222564 BAD96284 AK292139 BAF84828 AK300002 BAG61821 AK304378 BAG65216 AK307121 AK312512 BAG35413 AV713889 AY769947 AAX12524 BC011937 BC019103 AAH19103 BC020458 BC051292 AAH51292 BE935691 CK002866 CR450300 CAG29296 DB479224 DQ185042 ABD14422 XM_011519840 XP_011518142 XM_011519841 XP_011518143 NM_001307929 NP_001294858 NM_006360 NP_006351
Function Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2). {ECO:0000255|HAMAP-Rule:MF_03012, ECO:0000269|PubMed:15919898, ECO:0000269|PubMed:17403899}.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03012}.
Tissue Specificity Broadly expressed. {ECO:0000269|PubMed:15919898}.

eIF3M CRISPR/Cas9 KO Plasmid (h) - sc-405675 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3M HDR Plasmid (h) - sc-405675-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3M Double Nickase Plasmid (h) - sc-405675-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3M Double Nickase Plasmid (h2) - sc-405675-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3M CRISPR Activation Plasmid (h) - sc-405675-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3M CRISPR Activation Plasmid (h2) - sc-405675-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3M Lentiviral Activation Particles (h) - sc-405675-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3M Lentiviral Activation Particles (h2) - sc-405675-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3M siRNA (h) - sc-96834 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eIF3M shRNA Plasmid (h) - sc-96834-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eIF3M shRNA (h) Lentiviral Particles - sc-96834-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU088021 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7770 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7770 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

EIF3M siRNA (Human) - CRH7117 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EIF3M - MBS8229867 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EIF3M (NM_006360.4) - SHH284569 from Creative biogene

Category siRNA
Species Reactivities Human

EIF3M shRNA Plasmid (Human) - CHH7117 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EIF3M miRNA 3'UTR clone - MiUTR3H-10720 from Creative biogene

Species Reactivities Human
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