HAS2

Gene Symbol	HAS2
Entrez Gene	3037
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	hyaluronan synthase 2
Other Description	HA synthase 2|hyaluronate synthase 2|hyaluronic acid synthase 2
Swissprots	Q32MM3 Q92819
Accessions	CAJ87378 CAL40919 CAL44783 CAL47700 EAW92010 Q92819 AJ604570 AK297724 BAG60078 BC069353 AAH69353 BC109071 AAI09072 BC109072 AAI09073 U54804 AAC50692 XM_011517000 XP_011515302 XM_011517001 XP_011515303 XM_011517002 XP_011515304 XM_011517003 XP_011515305 NM_005328 NP_005319
Function	Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix (By similarity). {ECO:0000250}.
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in fibroblasts.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Hyaluronan synthase 2 protein fragment - ab158635 from Abcam Category Protein Source Wheat germ Species Human

HAS2 Blocking Peptide - LS-E7930 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Hyaluronan synthase 2 Protein - H00003037-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HAS2-Antibody-Center-Blocking-peptide - BP5687c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Hyaluronic acid synthase 2 / HAS2 - H00003037-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Hyaluronic acid synthase 2 / HAS2 - H00003037-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Hyaluronan Synthase 2 (HAS2) - RPF472Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Hyaluronan Synthase 2 (HAS2) - RPF472Hu01 from Cloud-clone Category Protein Source E.coli Species Human

HAS2 Peptide, Human - M34GP06841H from Creative Peptides Category Peptide Source Synthetic. Species Human

Hyaluronan synthase 2 Recombinant Protein Antigen - NBP2-58152PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Hyaluronan synthase 2 (HAS2), Recombinant Protein - MBS7016503 from MyBioSource Category Protein Prices $1,350.00, $2,335.00, $3,540.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Recombinant Human HAS2 Protein, GST-tagged - HAS2-4584H from Creative Biomart Category Protein Source Wheat Germ Species Human

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