HAS2

Gene Symbol HAS2
Entrez Gene 3037
Alt Symbol -
Species Human
Gene Type protein-coding
Description hyaluronan synthase 2
Other Description HA synthase 2|hyaluronate synthase 2|hyaluronic acid synthase 2
Swissprots Q32MM3 Q92819
Accessions CAJ87378 CAL40919 CAL44783 CAL47700 EAW92010 Q92819 AJ604570 AK297724 BAG60078 BC069353 AAH69353 BC109071 AAI09072 BC109072 AAI09073 U54804 AAC50692 XM_011517000 XP_011515302 XM_011517001 XP_011515303 XM_011517002 XP_011515304 XM_011517003 XP_011515305 NM_005328 NP_005319
Function Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in fibroblasts.

HAS2 (C-5) - sc-365263 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HAS2 (C-5): sc-365263. Western blot analysis of HAS2 expression in mouse embryo tissue extract.

HAS2 (H-60) - sc-66916 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

HAS2 (Y-14) - sc-34068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HAS2 (Y-14): sc-34068. Western blot analysis of HAS2 expression in mouse embryo tissue extract.

HAS2 (S-15) - sc-34067 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Hyaluronan synthase 2 antibody [4E7] - ab140671 from Abcam

Prices $394.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E7
Overlay histogram showing HeLa cells stained with ab140671 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab140671, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-HAS2 Antibody (clone 4E7) IHC-plus™ - LS-B9462 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4E7
Anti-HAS2 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-HAS2 Antibody (Internal, APC) - LS-C236100 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAS2 Antibody (Internal, AP) - LS-C236099 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAS2 Antibody (Internal, PE) - LS-C236105 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAS2 Antibody (Internal, Biotin) - LS-C236101 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAS2 Antibody (Internal, FITC) - LS-C236102 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAS2 Antibody (Internal, Azide-free, HRP) - LS-C249162 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAS2 Antibody (HRP) - LS-C318011 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HAS2 Antibody - LS-C318012 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HAS2 Antibody (FITC) - LS-C319002 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HAS2 Antibody (Biotin) - LS-C318540 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HAS2 Antibody (Internal) - LS-C321872 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Hyaluronan synthase 2 Antibody (4E7) - NBP2-37446 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E7
Western Blot: Hyaluronan synthase 2 Antibody (4E7) [NBP2-37446] - Western blot analysis using HAS2 mouse mAb against NTERA-2 (1), HEK293 (2) cell lysate.

HAS2 Antibody (OALA07571) - OALA07571 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4E7

HAS2 Antibody - middle region (OAAB03095) - OAAB03095 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

HAS2-antibody - AP50809 from Abgent, a WuXi AppTec company

Prices $295.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from 293 cell line and mouse heart tissue lysate, using HAS2 antibody, was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

HAS2-Antibody-Center - AP5687c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded H. kidney section using HAS2 Antibody (Center)(Cat#AP5687C). AP5687C was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.

RAG1-Antibody - AO1762a from Abgent, a WuXi AppTec company

Prices $385.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D9
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

HAS2-Antibody-Center - AW5442 from Abgent, a WuXi AppTec company

Prices $110.00, $325.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HAS2 Antibody (Center) at 1:1000 dilution Lane 1: human heart lysates Lane 2: mouse heart lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 64 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

HAS2 antibody [4E7] - GTX60647 from GeneTex

Prices $319.00
Sizes 100 μg
Host Mouse
Clonality Monoclonal
Clone 4E7
Anti-HAS2 antibody [4E7] used in Western blot. GTX60647
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