CYBRD1

Gene Symbol CYBRD1
Entrez Gene 79901
Alt Symbol CYB561A2, DCYTB, FRRS3
Species Human
Gene Type protein-coding
Description cytochrome b reductase 1
Other Description cytochrome b561 family, member A2|duodenal cytochrome b|ferric-chelate reductase 3
Swissprots Q6KC17 Q6ZR51 Q9H5G5 B2RE79 B4DWD7 Q6KC16 Q9H0Q8 Q6P147 Q53TN4
Accessions AAY14730 ABF47090 CAG29366 CAG29367 EAX11210 Q53TN4 AK026654 AK027115 BAB15661 AK128495 BAC87466 AK225459 AK291731 BAF84420 AK301485 BAG62999 AK316588 BAG38176 AL136693 CAB66628 AL834483 BC016900 BC065290 AAH65290 BP418883 CB266594 CB266845 CX866825 DA211209 DB000953 DB235339 HQ257890 ADR82645 NM_001127383 NP_001120855 NM_001256909 NP_001243838 NM_024843 NP_079119
Function Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. {ECO:0000269|PubMed:16521311, ECO:0000269|PubMed:16521312, ECO:0000269|PubMed:17068337, ECO:0000269|PubMed:19673882}.
Subcellular Location Membrane {ECO:0000269|PubMed:12949720}; Multi-pass membrane protein {ECO:0000269|PubMed:12949720}.
Tissue Specificity Present in erythrocyte membranes (at protein level). Also expressed in respiratory epithelium. {ECO:0000269|PubMed:16510471, ECO:0000269|PubMed:17068337}.
Top Pathways Mineral absorption

CYBRD1 CRISPR/Cas9 KO Plasmid (h) - sc-405726 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYBRD1 HDR Plasmid (h) - sc-405726-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYBRD1 Double Nickase Plasmid (h) - sc-405726-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYBRD1 Double Nickase Plasmid (h2) - sc-405726-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYBRD1 CRISPR Activation Plasmid (h) - sc-405726-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYBRD1 CRISPR Activation Plasmid (h2) - sc-405726-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYBRD1 Lentiviral Activation Particles (h) - sc-405726-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYBRD1 Lentiviral Activation Particles (h2) - sc-405726-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYBRD1 siRNA (h) - sc-94877 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYBRD1 shRNA Plasmid (h) - sc-94877-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYBRD1 shRNA (h) Lentiviral Particles - sc-94877-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN6858 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6858 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CYBRD1 siRNA (Human) - CRJ2654 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYBRD1 - MBS8231233 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CYBRD1 (NM_024843.3) - SHH272673 from Creative biogene

Category siRNA
Species Reactivities Human

Human CYBRD1 siRNA - orb273155 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYBRD1 shRNA Plasmid (Human) - CHJ2654 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CYBRD1 miRNA 3'UTR clone - MiUTR4H-TG02511 from Creative biogene

Species Reactivities Human
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