CYBRD1

Gene Symbol CYBRD1
Entrez Gene 79901
Alt Symbol CYB561A2, DCYTB, FRRS3
Species Human
Gene Type protein-coding
Description cytochrome b reductase 1
Other Description cytochrome b561 family, member A2|duodenal cytochrome b|ferric-chelate reductase 3
Swissprots Q6KC17 Q6ZR51 Q9H5G5 B2RE79 B4DWD7 Q6KC16 Q9H0Q8 Q6P147 Q53TN4
Accessions AAY14730 ABF47090 CAG29366 CAG29367 EAX11210 Q53TN4 AK026654 AK027115 BAB15661 AK128495 BAC87466 AK225459 AK291731 BAF84420 AK301485 BAG62999 AK316588 BAG38176 AL136693 CAB66628 AL834483 BC016900 BC065290 AAH65290 BP418883 CB266594 CB266845 CX866825 DA211209 DB000953 DB235339 HQ257890 ADR82645 NM_001127383 NP_001120855 NM_001256909 NP_001243838 NM_024843 NP_079119
Function Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. {ECO:0000269|PubMed:16521311, ECO:0000269|PubMed:16521312, ECO:0000269|PubMed:17068337, ECO:0000269|PubMed:19673882}.
Subcellular Location Membrane {ECO:0000269|PubMed:12949720}; Multi-pass membrane protein {ECO:0000269|PubMed:12949720}.
Tissue Specificity Present in erythrocyte membranes (at protein level). Also expressed in respiratory epithelium. {ECO:0000269|PubMed:16510471, ECO:0000269|PubMed:17068337}.
Top Pathways Mineral absorption

CYBRD1 (N-12) - sc-161024 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYBRD1 (N-12): sc-161024. Western blot analysis of CYBRD1 expression in mouse lung tissue extract.

CYBRD1 (G-13) - sc-161021 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYBRD1 (S-13) - sc-161025 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Cytochrome b reductase 1 antibody - ab66048 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome b reductase 1 antibody (ab66048) at 1 µg/ml + A20 (Mouse B lymphoma cell line) Whole Cell Lysate (ab7180) at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Cytochrome b reductase 1 antibody - ab28758 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ICC/IF image of adult mouse gut section stained with (ab28758) . Tissue was perfusion fixed with 4% PFA. The sections were incubated in 10% normal donkey serum in 0.1% PBS- and triton X100 for 1h to permeabilise the cells and block non-specific protein-protein interactions. The sections were then incubated with the antibody (ab28758) @ 1µg/ml) overnight @ 4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.See Abreview

Anti-Cytochrome b reductase 1 antibody - ab111997 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab111997 at 2.5 µg/ml staining Cytochrome b reductase 1 in Formalin-Fixed, Paraffin-Embedded Human Small Intestine by Immunohistochemistry.

Anti-Cytochrome b reductase 1 antibody - C-terminal - ab155214 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Cytochrome b reductase 1 antibody - C-terminal (ab155214) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-DCYTB / CYBRD1 Antibody (C-Terminus) - LS-C14951 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-DCYTB / CYBRD1 Antibody (C-Terminus) - LS-C14952 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DCYTB / CYBRD1 Antibody (aa273-286) IHC-plus™ - LS-B4448 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-CYBRD1 / DCYTB antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4448 concentration 2.5 ug/ml.

Cytochrome b reductase 1 Antibody - NBP1-84291 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Cytochrome b reductase 1 Antibody [NBP1-84291] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

Cytochrome b reductase 1 Antibody - NB300-914 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: Cytochrome b reductase 1 Antibody [NB300-914] - (2.5ug/ml) IHC staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Cytochrome b reductase 1 Antibody - NBP2-16075 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Cytochrome b reductase 1 Antibody [NBP2-16075] - Sample (30 ug of whole cell lysate) A: H1299 12% SDS PAGE gel, diluted at 1:1000.

CYBR1 Polyclonal Antibody - bs-8297R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-CYBR1 Polyclonal Antibody, Unconjugated(bs-8297R) at 1:200, followed by conjugation to the secondary antibody and DAB staining

Anti-CYBRD1 antibody produced in rabbit - HPA014757 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CYBRD1: <B>Cat. No. HPA014757</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon shows strong cytoplasmic and membranous positivity in glandular cells.

Anti-CYBRD1 (C-terminal) antibody produced in rabbit - SAB2700288 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYBRD1 (C-terminal): <B>Cat. No. SAB2700288</B>: Western Blot analysis of CYBRD1 in extracts from <B>Lanes</B><BR/>A. H1299 using <B>Cat. No. SAB2700288</B> at a 1:1000 dilution.

Anti-CYBRD1 (C-terminal) antibody produced in goat - SAB2501800 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Cytochrome-b-reductase-1-Antibody-C-Term - AF2429a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2429a (2.5 µg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Cytochrome b reductase 1 antibody [C2C3], C-term - GTX104793 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome b reductase 1 antibody [C2C3], C-term used in Western blot. GTX104793

Cytochrome b reductase 1 antibody, C-term - GTX89592 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-Cytochrome b reductase 1 antibody, C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX89592

CYBRD1 Antibody (OAEB00128) - OAEB00128 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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