COPB2

Gene Symbol COPB2
Entrez Gene 9276
Alt Symbol beta'-COP
Species Human
Gene Type protein-coding
Description coatomer protein complex, subunit beta 2 (beta prime)
Other Description beta'-coat protein|betaprime-COP|coatomer binding complex, beta prime subunit|coatomer subunit beta'|p102
Swissprots B4DZI8 P35606
Accessions CAJ42726 EAW79039 EAW79040 P35606 AK128561 AK302943 BAG64100 AK304219 BAG65091 BC000326 AAH00326 DC347783 DC385126 JF432305 ADZ15522 X70476 CAA49900 XM_011513317 XP_011511619 NM_004766 NP_004757 NR_023350
Function The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Shows only a slight preference for the cis-Golgi apparatus, compared with the trans-Golgi. {ECO:0000250}.

β'-COP (K-19) - sc-23167 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
β'-COP (K-19): sc-23167. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lower stomach tissue showing cytoplasmic and nuclear staining of glandular cells.

β'-COP (V-19) - sc-13332 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
β' Antibody (V-19): sc-13332. Immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder tissue showing cytoplasmic and membrane staining of glandular cells.

Anti-beta COP I antibody - C-terminal - ab139131 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-beta COP I antibody - C-terminal (ab139131) at 1/100 dilution + HeLa cell line lysates at 35 µgdeveloped using the ECL technique

Anti-Beta-COP / COPB2 Antibody (aa814-843) - LS-C159392 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
COPB2 Antibody western blot of mouse stomach tissue lysates (35 ug/lane). The COPB2 antibody detected the COPB2 protein (arrow).

Anti-Beta-COP / COPB2 Antibody (aa494-511) IHC-plus™ - LS-B2677 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-COPB2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2677 concentration 5 ug/ml.

Anti-Beta-COP / COPB2 Antibody - LS-C346386 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of U20S cell using COPB2 antibody. Blue: DAPI for nuclear staining.

Anti-Beta-COP / COPB2 Antibody (aa814-843, Biotin) - LS-C208554 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Beta-COP / COPB2 Antibody (aa814-843, FITC) - LS-C208555 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Beta-COP / COPB2 Antibody (aa814-843, APC) - LS-C208553 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Beta-COP / COPB2 Antibody (aa814-843, Azide-free, HRP) - LS-C208556 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Beta-COP / COPB2 Antibody (aa814-843, PE) - LS-C208557 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Beta-COP / COPB2 Antibody (aa814-843, AP) - LS-C208552 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Beta-COP / COPB2 Antibody (aa814-843) - LS-C320523 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

COPB2 Antibody (M3A5) - NB600-102 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone M3A5

COPB2 Antibody - NBP1-88651 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal

COPB2 Antibody - NB120-2915 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: COPB2 Antibody [NB120-2915] - Analysis of Beta-COP from PC-12 cell lysates.

Anti-COPB2 (831-845) antibody produced in rabbit - SAB1104663 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human COPB2 was separated on SDS-PAGE, blotted with Anti-COPB2 (831-845) (<B>Cat. No. SAB1104663</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

Anti-COPB2 (396-410) antibody produced in rabbit - SAB1104662 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human COPB2 was separated on SDS-PAGE, blotted with Anti-COPB2 (396-410) (<B>Cat. No. SAB1104662</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

Anti-COPB2 antibody produced in rabbit - HPA036867 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-COPB2: <B>Cat. No. HPA036867</B>: Immunohistochemical staining of human stomach shows strong granular cytoplasmic positivity in glandular cells.

COPB2-Antibody-C-term - AP18930b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
COPB2 Antibody (C-term) (Cat. #AP18930b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the COPB2 antibody detected the COPB2 protein (arrow).

beta COP antibody - GTX22915 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-beta COP antibody used in Western blot. GTX22915

COPB2 Antibody - C-terminal region (OAAB14468) - OAAB14468 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti -COPB2, CT (COPB2, Coatomer subunit beta', Beta'-coat protein, p102) - 034114 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -COPB2, CT (COPB2, Coatomer subunit beta', Beta'-coat protein, p102) (AP) - 034114-AP from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -COPB2, CT (COPB2, Coatomer subunit beta', Beta'-coat protein, p102) (APC) - 034114-APC from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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