COPB2

Gene Symbol	COPB2
Entrez Gene	9276
Alt Symbol	beta'-COP
Species	Human
Gene Type	protein-coding
Description	coatomer protein complex, subunit beta 2 (beta prime)
Other Description	beta'-coat protein|betaprime-COP|coatomer binding complex, beta prime subunit|coatomer subunit beta'|p102
Swissprots	B4DZI8 P35606
Accessions	CAJ42726 EAW79039 EAW79040 P35606 AK128561 AK302943 BAG64100 AK304219 BAG65091 BC000326 AAH00326 DC347783 DC385126 JF432305 ADZ15522 X70476 CAA49900 XM_011513317 XP_011511619 NM_004766 NP_004757 NR_023350
Function	The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Shows only a slight preference for the cis-Golgi apparatus, compared with the trans-Golgi. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

beta COP I peptide - ab4933 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human beta COP I full length protein - ab131885 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human beta COP I protein fragment - ab160413 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

COPB2 Recombinant Protein - H00009276-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

COPB2 Partial Recombinant Protein - H00009276-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

COPB2-Antibody-C-term-Blocking-Peptide - BP18930b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Coatomer subunit beta' / COPB2 - H00009276-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Coatomer subunit beta' / COPB2 - H00009276-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Coatomer subunit beta' / COPB2 - H00009276-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Coatomer subunit beta' / COPB2 - H00009276-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

COPB2 fusion protein - Ag6498 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

COPB2 fusion protein - Ag6551 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human COPB2, GST-tagged - COPB2-11455H from Creative Biomart Category Protein Source E.coli Species Human

Coatomer subunit beta' / COPB2 (transcript variant 1) - TP301789 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

COPB2 Recombinant Protein Antigen - NBP1-88651PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

COPB2 Peptide, Human - M34GP03495H from Creative Peptides Category Peptide Source Synthetic. Species Human

COPB2 Recombinant Protein Antigen - NBP2-54952PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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