KCNH2

Gene Symbol KCNH2
Entrez Gene 3757
Alt Symbol ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1, LQT2, SQT1
Species Human
Gene Type protein-coding
Description potassium channel, voltage gated eag related subfamily H, member 2
Other Description eag homolog|eag-related protein 1|ether-a-go-go-related gene potassium channel 1|ether-a-go-go-related potassium channel protein|ether-a-go-go-related protein 1|potassium voltage-gated channel subfamily H member 2|potassium voltage-gated channel, subfamily H (eag-related), member 2|voltage-gated potassium channel subunit Kv11.1
Swissprots O75418 O75680 Q9BUT7 D3DX04 C4PFH9 Q9BT72 Q9H3P0 A5H1P7 Q12809 Q708S9
Accessions AAQ91589 AAQ91590 AAQ91591 AAQ91592 AAQ91593 AAQ91594 AAQ91595 AAQ91596 AAQ91597 AAQ91598 AAQ91599 AAQ91600 AAQ91601 AAS07566 AAS07567 ABQ01243 ABW98495 ACN88550 ACT31321 AEL63844 AFR51950 BAA37096 CAA09232 CAJ13411 CAJ13412 CAJ18800 CAJ18801 EAL24491 EAL24492 EAL24493 EAW54071 EAW54072 EAW54073 EAW54074 EAW54075 Q12809 AB044806 BAB19682 AF052728 AAC69709 AF363636 AAL37559 AJ512214 CAD54447 AJ609614 CAE82156 AY927502 BC001914 AAH01914 BC004311 AAH04311 BC127672 BC127673 AAI27674 BC167862 AAI67862 BG683210 BM674996 BQ478289 BQ890248 BT007336 AAP36000 DQ120124 AAZ40507 DQ120125 AAZ40508 DQ525913 ABF71886 FJ938021 ACR24650 U04270 AAA62473 XM_011516185 XP_011514487 XM_011516186 XP_011514488 NM_000238 NP_000229 NM_001204798 NP_001191727 NM_172056 NP_742053 NM_172057 NP_742054
Function Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation. {ECO:0000269|PubMed:18559421}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:18559421, ECO:0000269|PubMed:19412172}; Multi-pass membrane protein {ECO:0000269|PubMed:18559421, ECO:0000269|PubMed:19412172}.
Tissue Specificity Highly expressed in heart and brain. Isoforms USO are frequently overexpressed in cancer cells. {ECO:0000269|PubMed:18559421}.

hERG1a (D1Y2J) Rabbit mAb - 12889 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D1Y2J
Western blot analysis of extracts from K-562 and F11 cells using hERG1a (D1Y2J) Rabbit mAb.

HERG (F-12) - sc-377388 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HERG (F-12): sc-377388. Western blot analysis of HERG expression in IMR-32 (A), K-562 (B), F9 (C) and EOC 20 (D) whole cell lysates.

HERG (C-20) - sc-15968 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HERG (C-20): sc-15968. Western blot analysis of HERG expression in non-transfected: sc-110760 (A) and human HERG transfected: sc-158600 (B) 293 whole cell lysates.

HERG (H-175) - sc-20130 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HERG (H-175): sc-20130. Western blot analysis of HERG expression in EOC 20 (A) and EOC 13.31 (B) whole cell lysates.

HERG (N-20) - sc-15966 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HERG (N-20): sc-15966. Western blot analysis of HERG expression in EOC 20 (A) and EOC 13.31 (B) whole cell lysates and rat (C) and mouse (D) heart tissue extracts.

Anti-KCNH2 antibody - ab196301 from Abcam

Prices $376.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of paraffin embedded, formalin fixed Human heart tissue labeling KCNH2 using ab196301 at 1/200 dilution.

Anti-KCNH2 antibody - ab192500 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNH2 antibody - C-terminal - ab81160 from Abcam

Prices $370.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody - LS-C341512 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (aa895-944) - LS-C145542 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KCNH2 / Kv11.1 antibody LS-C145542 Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.

Anti-KCNH2 / HERG Antibody (aa886-899) - LS-C332303 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using KCNH2 antibody.

Anti-KCNH2 / HERG Antibody - LS-C331431 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of CEM cell line, using KCNH2 antibody.

Anti-KCNH2 / HERG Antibody - LS-C137022 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (aa861-888) - LS-C165420 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of KCNH2 Antibody in CEM cell line lysates (35 ug/lane). KCNH2 (arrow) was detected using the purified antibody.

Anti-KCNH2 / HERG Antibody (C-Terminus) - LS-C7388 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (Internal, DY650) - LS-C142555 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (Internal, HRP) - LS-C142557 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (Internal, DY488) - LS-C142556 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (Internal, DY550) - LS-C142558 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (C-Terminus) - LS-C144865 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (C-Terminus) - LS-C153515 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (AP) - LS-C225568 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (Biotin) - LS-C225570 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (APC) - LS-C225569 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNH2 / HERG Antibody (FITC) - LS-C225571 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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