KCNH2

Gene Symbol KCNH2
Entrez Gene 3757
Alt Symbol ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1, LQT2, SQT1
Species Human
Gene Type protein-coding
Description potassium channel, voltage gated eag related subfamily H, member 2
Other Description eag homolog|eag-related protein 1|ether-a-go-go-related gene potassium channel 1|ether-a-go-go-related potassium channel protein|ether-a-go-go-related protein 1|potassium voltage-gated channel subfamily H member 2|potassium voltage-gated channel, subfamily H (eag-related), member 2|voltage-gated potassium channel subunit Kv11.1
Swissprots O75418 O75680 Q9BUT7 D3DX04 C4PFH9 Q9BT72 Q9H3P0 A5H1P7 Q12809 Q708S9
Accessions AAQ91589 AAQ91590 AAQ91591 AAQ91592 AAQ91593 AAQ91594 AAQ91595 AAQ91596 AAQ91597 AAQ91598 AAQ91599 AAQ91600 AAQ91601 AAS07566 AAS07567 ABQ01243 ABW98495 ACN88550 ACT31321 AEL63844 AFR51950 BAA37096 CAA09232 CAJ13411 CAJ13412 CAJ18800 CAJ18801 EAL24491 EAL24492 EAL24493 EAW54071 EAW54072 EAW54073 EAW54074 EAW54075 Q12809 AB044806 BAB19682 AF052728 AAC69709 AF363636 AAL37559 AJ512214 CAD54447 AJ609614 CAE82156 AY927502 BC001914 AAH01914 BC004311 AAH04311 BC127672 BC127673 AAI27674 BC167862 AAI67862 BG683210 BM674996 BQ478289 BQ890248 BT007336 AAP36000 DQ120124 AAZ40507 DQ120125 AAZ40508 DQ525913 ABF71886 FJ938021 ACR24650 U04270 AAA62473 XM_011516185 XP_011514487 XM_011516186 XP_011514488 NM_000238 NP_000229 NM_001204798 NP_001191727 NM_172056 NP_742053 NM_172057 NP_742054
Function Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation. {ECO:0000269|PubMed:18559421}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:18559421, ECO:0000269|PubMed:19412172}; Multi-pass membrane protein {ECO:0000269|PubMed:18559421, ECO:0000269|PubMed:19412172}.
Tissue Specificity Highly expressed in heart and brain. Isoforms USO are frequently overexpressed in cancer cells. {ECO:0000269|PubMed:18559421}.

HERG CRISPR/Cas9 KO Plasmid (h) - sc-401143 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HERG HDR Plasmid (h) - sc-401143-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HERG Double Nickase Plasmid (h) - sc-401143-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HERG Double Nickase Plasmid (h2) - sc-401143-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HERG CRISPR Activation Plasmid (h) - sc-401143-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HERG CRISPR Activation Plasmid (h2) - sc-401143-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HERG Lentiviral Activation Particles (h) - sc-401143-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HERG Lentiviral Activation Particles (h2) - sc-401143-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HERG siRNA (h) - sc-42497 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HERG shRNA Plasmid (h) - sc-42497-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HERG shRNA (h) Lentiviral Particles - sc-42497-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Kv11.1 RNAi - H00003757-R07 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Kv11.1 RNAi - H00003757-R08 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU080951 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1661 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1661 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12999 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12999

KCNH2 siRNA (Human) - CRH2533 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Kv11.1 RNAi - H00003757-R09 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KCNH2, siRNA - MBS8240667 from MyBioSource

Category siRNA
Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KCNH2 (NM_000238.3) - SHH323047 from Creative biogene

Category siRNA
Species Reactivities Human

Human KCNH2 siRNA - orb263035 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KCNH2 shRNA Plasmid (Human) - CHH2533 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KCNH2 miRNA 3'UTR clone - MiUTR3H-01334 from Creative biogene

Species Reactivities Human

KCNH2 miRNA 3'UTR clone - MiUTR3H-01335 from Creative biogene

Species Reactivities Human
Search more