| Gene Symbol |
ATXN10
|
| Entrez Gene |
25814
|
| Alt Symbol |
E46L, HUMEEP, SCA10
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ataxin 10
|
| Other Description |
ataxin-10|brain protein E46 homolog|spinocerebellar ataxia type 10 protein
|
| Swissprots |
Q6I9X4 O15009 Q9UBB4 O14998 A6NLC4 B4DG05
|
| Accessions |
EAW73392 EAW73393 Q9UBB4 AF086923 AAP97153 AF119662 AAF17219 AK025734 AK095309 AK294348 BAG57616 AL050282 CAB43383 AL137374 CAB70715 BC007508 AAH07508 BI597255 CR456568 CAG30454 CR457381 CAG33662 DB035174 DB548216 DQ893240 ABM84166 DQ896570 ABM87569 R43701 NM_001167621 NP_001161093 NM_013236 NP_037368
|
| Function |
Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000269|PubMed:16498633}.
|
| Tissue Specificity |
Expressed in the central nervous system. {ECO:0000269|PubMed:15201271}.
|
![Western Blot: Ataxin-10 Overexpression Lysate (Adult Normal) [NBP2-11465] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Ataxin-10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2013_Ataxin-10%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-11465-img0001.jpg)
![Western Blot: Ataxin-10 Overexpression Lysate (Adult Normal) [NBP2-10349] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Ataxin-10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2748_Ataxin-10%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10349-img0001.jpg)