Gene Symbol | ATXN10 |
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Entrez Gene | 25814 |
Alt Symbol | E46L, HUMEEP, SCA10 |
Species | Human |
Gene Type | protein-coding |
Description | ataxin 10 |
Other Description | ataxin-10|brain protein E46 homolog|spinocerebellar ataxia type 10 protein |
Swissprots | Q6I9X4 O15009 Q9UBB4 O14998 A6NLC4 B4DG05 |
Accessions | EAW73392 EAW73393 Q9UBB4 AF086923 AAP97153 AF119662 AAF17219 AK025734 AK095309 AK294348 BAG57616 AL050282 CAB43383 AL137374 CAB70715 BC007508 AAH07508 BI597255 CR456568 CAG30454 CR457381 CAG33662 DB035174 DB548216 DQ893240 ABM84166 DQ896570 ABM87569 R43701 NM_001167621 NP_001161093 NM_013236 NP_037368 |
Function | Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. {ECO:0000250}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000269|PubMed:16498633}. |
Tissue Specificity | Expressed in the central nervous system. {ECO:0000269|PubMed:15201271}. |
Ataxin-10 CRISPR/Cas9 KO Plasmid (h) - sc-406001 from Santa Cruz Biotechnology
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Ataxin-10 HDR Plasmid (h) - sc-406001-HDR from Santa Cruz Biotechnology
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Ataxin-10 Double Nickase Plasmid (h) - sc-406001-NIC from Santa Cruz Biotechnology
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Ataxin-10 Double Nickase Plasmid (h2) - sc-406001-NIC-2 from Santa Cruz Biotechnology
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Ataxin-10 CRISPR Activation Plasmid (h) - sc-406001-ACT from Santa Cruz Biotechnology
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Ataxin-10 CRISPR Activation Plasmid (h2) - sc-406001-ACT-2 from Santa Cruz Biotechnology
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Ataxin-10 Lentiviral Activation Particles (h) - sc-406001-LAC from Santa Cruz Biotechnology
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Ataxin-10 Lentiviral Activation Particles (h2) - sc-406001-LAC-2 from Santa Cruz Biotechnology
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Ataxin-10 siRNA (h) - sc-60218 from Santa Cruz Biotechnology
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Ataxin-10 shRNA Plasmid (h) - sc-60218-SH from Santa Cruz Biotechnology
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Ataxin-10 shRNA (h) Lentiviral Particles - sc-60218-V from Santa Cruz Biotechnology
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Ataxin-10 RNAi - H00025814-R01 from Novus Biologicals
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MISSION® esiRNA - EHU129971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3758 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3758 from Sigma-Aldrich
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ATXN10 siRNA (Human) - CRH8514 from Cohesion Biosciences
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ATXN10 - MBS8229030 from MyBioSource
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shRNA set against Human ATXN10 (NM_013236.3) - SHH243534 from Creative biogene
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ATXN10 shRNA Plasmid (Human) - CHH8514 from Cohesion Biosciences
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ATXN10 miRNA 3'UTR clone - MiUTR3H-11675 from Creative biogene
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