Gene Symbol | ATXN10 |
---|---|
Entrez Gene | 25814 |
Alt Symbol | E46L, HUMEEP, SCA10 |
Species | Human |
Gene Type | protein-coding |
Description | ataxin 10 |
Other Description | ataxin-10|brain protein E46 homolog|spinocerebellar ataxia type 10 protein |
Swissprots | Q6I9X4 O15009 Q9UBB4 O14998 A6NLC4 B4DG05 |
Accessions | EAW73392 EAW73393 Q9UBB4 AF086923 AAP97153 AF119662 AAF17219 AK025734 AK095309 AK294348 BAG57616 AL050282 CAB43383 AL137374 CAB70715 BC007508 AAH07508 BI597255 CR456568 CAG30454 CR457381 CAG33662 DB035174 DB548216 DQ893240 ABM84166 DQ896570 ABM87569 R43701 NM_001167621 NP_001161093 NM_013236 NP_037368 |
Function | Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. {ECO:0000250}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000269|PubMed:16498633}. |
Tissue Specificity | Expressed in the central nervous system. {ECO:0000269|PubMed:15201271}. |