MIIP

Gene Symbol MIIP
Entrez Gene 60672
Alt Symbol IIP45
Species Human
Gene Type protein-coding
Description migration and invasion inhibitory protein
Other Description IGFBP2-binding protein|invasion-inhibitory protein 45|migration and invasion-inhibitory protein
Swissprots Q96HU6 C0KL22 Q5JXC2 Q9H839 Q9HA00
Accessions EAW71729 Q5JXC2 AK022500 BAB14062 AK024020 BAB14781 AK095928 AW196459 BC008068 AAH08068 BG536799 BI828925 FJ618905 ACM90320 HQ447804 ADQ32288 XM_005263487 XP_005263544 XM_011541895 XP_011540197 XM_011541896 XP_011540198 NM_021933 NP_068752 NM_001025374
Function Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1. Exhibits opposing effects to IGFBP2 on cell invasion. {ECO:0000269|PubMed:14617774}.
Tissue Specificity Ubiquitous. Isoform 1 is expressed in brain but underexpressed in glioma tissues, at protein level. Isoform 2 is not detected in normal organs, but is expressed in gliomas with increasing levels with glioma progression. On the contrary, at protein level, isoform 2 is not detected in gliomas, suggesting that this isoform is unstable in glioma cells. {ECO:0000269|PubMed:14617774}.

IIp45 (E-16) - sc-243066 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IIp45 (N-16) - sc-243064 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-MIIP antibody - ab103380 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MIIP antibody (ab103380) at 1/100 dilution + ZR-75-1 cell lysate at 35 µg

Anti-MIIP antibody - ab167197 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-MIIP antibody (ab167197) at 1 µg/mlLane 1 : Lysate of 293T cells transfected with MIIPLane 2 : Lysate of 293T cells (non-transfected)Lysates/proteins at 15 µl per lane.SecondaryGoat anti-mouse HRP conjugated antibody at 1/2500 dilution

Anti-IIP45 / MIIP Antibody (aa275-303, AP) - LS-C237652 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IIP45 / MIIP Antibody (aa275-303, APC) - LS-C237653 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IIP45 / MIIP Antibody (aa275-303, Biotin) - LS-C237654 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IIP45 / MIIP Antibody (aa275-303, PE) - LS-C237657 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IIP45 / MIIP Antibody (aa275-303, FITC) - LS-C237655 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IIP45 / MIIP Antibody (aa275-303, Azide-free, HRP) - LS-C248820 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IIP45 / MIIP Antibody (aa280-320) - LS-C323005 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IIP45 / MIIP Antibody (aa275-303) - LS-C164196 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of MIIP Antibody in ZR-75-1 cell line lysates (35 ug/lane). MIIP (arrow) was detected using the purified antibody.

RP5-1077B9.4 Antibody - NBP1-87394 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MIIP (46-60) antibody produced in rabbit - SAB1101870 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human MIIP was separated on SDS-PAGE, blotted with Anti- MIIP (46-60) (<B>Cat. No. SAB1101870</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000 <BR/>2. Antibody dilution 1:1,000 + MIIP immunizing peptide (human, 46-60)

Anti-MIIP antibody produced in rabbit - HPA044948 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MIIP: <B>Cat. No. HPA044948</B>: Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.

Anti-RP5-1077B9.4 antibody produced in mouse - SAB1407840 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RP5-1077B9.4: <B>Cat. No. SAB1407840</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~42.7 kDa using RP5~1077B9.4 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

MIIP Antibody - C-terminal region (OAAB02474) - OAAB02474 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

MIIP-Antibody-C-term - AP5059b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of MIIP Antibody (C-term) (Cat. #AP5059b) in ZR-75-1 cell line lysates (35ug/lane).MIIP (arrow) was detected using the purified Pab.

MIIP antibody - GTX51659 from GeneTex

Prices $319.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Anti-MIIP antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX51659

MIIP antibody - orb100491 from Biorbyt

Prices $60.00, $128.00, $255.00, $340.00
Sizes 5 μg (Trial size), 20 μg (Trial size), 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human brain glioma tissue using MIIP antibody.

MIIP Antibody (OABF01614) - OABF01614 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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