Gene Symbol | NRGN |
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Entrez Gene | 4900 |
Alt Symbol | RC3, hng |
Species | Human |
Gene Type | protein-coding |
Description | neurogranin (protein kinase C substrate, RC3) |
Other Description | calmodulin-binding protein|neurogranin|ng|protein kinase C substrate |
Swissprots | Q92686 |
Accessions | CAA67532 CAA67533 CAA75343 CAC37631 EAW67593 EAW67594 Q92686 BC002835 AAH02835 BM923818 BT007325 AAP35989 DB474181 U89165 AAB49458 Y09689 CAA70867 NM_001126181 NP_001119653 NM_006176 NP_006167 |
Function | Acts as a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity). {ECO:0000250}. |
Tissue Specificity | In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease. {ECO:0000269|PubMed:9329454}. |
Human Neurogranin full length protein - ab114665 from Abcam
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Human Neurogranin full length protein - ab181939 from Abcam
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NRGN / Neurogranin Antibody Blocking Peptide - LS-E11983 from LifeSpan Bioscience
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NRGN / Neurogranin Antibody Blocking Peptide - LS-E27200 from LifeSpan Bioscience
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Recombinant Human Neurogranin Protein - H00004900-P01 from Novus Biologicals
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Neurogranin blocking peptide - GTX88301-PEP from GeneTex
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Human NRGN protein - orb80567 from Biorbyt
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NRGN protein (His tag) - 80R-3867 from Fitzgerald
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Neurogranin Peptide - AC21-2020-P from Abcore
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Neurogranin (1-78, His-tag) - AR51554PU-N from Acris Antibodies
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Neurogranin (1-78, His-tag) - AR51554PU-S from Acris Antibodies
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NRGN, 1-78aa, Human, His tag, E.coli - 01-P2734 from ARP American Research Products
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Neurogranin Peptide - 42-219P from ProSci
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NRGN fusion protein - ag0676 from Proteintech Group
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NRGN fusion protein - Ag23330 from Proteintech Group
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Neurogranin (28-43) - 101471 from NeoScientific
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Recombinant Neurogranin (NRGN) - RPA404Hu01 from Uscn Life Science Inc.
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Recombinant Neurogranin (NRGN) - RPA404Hu01 from Cloud-clone
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BSA Conjugated Asymmetrical Dimethylarginine (ADMA) - CPB301Ge11 from Cloud-clone
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OVA Conjugated Asymmetrical Dimethylarginine (ADMA) - CPB301Ge21 from Cloud-clone
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Recombinant Human Neurogranin(NRGN) - CSB-YP849776HU CSB-EP849776HU CSB-BP849776HU CSB-MP849776HU from Cusabio
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NRGN, 1-78aa, Human, His tag, E.coli - ATGP2734 from ATGen
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Neurogranin Protein (Recombinant) - abx262390 from Abbexa
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NRGN Protein - abx163553 from Abbexa
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Neurogranin (transcript variant 1) - TP301209 from Acris Antibodies
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