RNF19B

Gene Symbol RNF19B
Entrez Gene 127544
Alt Symbol IBRDC3, NKLAM
Species Human
Gene Type protein-coding
Description ring finger protein 19B
Other Description E3 ubiquitin-protein ligase RNF19B|IBR domain-containing protein 3|natural killer lytic-associated molecule
Swissprots Q6P6A4 Q0VG77 B7ZLB2 Q8WUF3 E9PAW6 Q5TH45 Q8N2S8 G3XA82 Q6ZMZ0 Q5TH44
Accessions CAF85699 EAX07489 EAX07490 EAX07491 Q6ZMZ0 AA194237 AK074486 BAC11017 AK131439 BAD18585 BC020595 AAH20595 BC062374 AAH62374 BC113560 AAI13561 BC143687 AAI43688 DA630289 XM_006710356 XP_006710419 XM_006710357 XP_006710420 XM_006710358 XP_006710421 NM_001127361 NP_001120833 NM_001300826 NP_001287755 NM_153341 NP_699172
Function E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. {ECO:0000269|PubMed:10438909, ECO:0000269|PubMed:16709802}.
Subcellular Location Cytoplasmic granule membrane {ECO:0000269|PubMed:10438909}; Multi-pass membrane protein {ECO:0000269|PubMed:10438909}.
Tissue Specificity Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells. Present in natural killer cells (at protein level). {ECO:0000269|PubMed:10438909, ECO:0000269|PubMed:10912506}.

NKLAM CRISPR/Cas9 KO Plasmid (h) - sc-409031 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NKLAM HDR Plasmid (h) - sc-409031-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NKLAM Double Nickase Plasmid (h) - sc-409031-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NKLAM Double Nickase Plasmid (h2) - sc-409031-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NKLAM CRISPR Activation Plasmid (h) - sc-409031-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NKLAM CRISPR Activation Plasmid (h2) - sc-409031-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NKLAM Lentiviral Activation Particles (h) - sc-409031-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NKLAM Lentiviral Activation Particles (h2) - sc-409031-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NKLAM siRNA (h) - sc-88628 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NKLAM shRNA Plasmid (h) - sc-88628-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NKLAM shRNA (h) Lentiviral Particles - sc-88628-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU078201 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18413 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18413 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

RNF19B siRNA (Human) - CRJ4921 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RNF19B - MBS8214820 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RNF19B (NM_153341.2) - SHH397076 from Creative biogene

Category siRNA
Species Reactivities Human

Human RNF19B siRNA - orb275422 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RNF19B shRNA Plasmid (Human) - CHJ4921 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RNF19B miRNA 3'UTR clone - MiUTR3H-11521 from Creative biogene

Species Reactivities Human

RNF19B miRNA 3'UTR clone - MiUTR3H-11522 from Creative biogene

Species Reactivities Human
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