SNRNP70

Gene Symbol	SNRNP70
Entrez Gene	6625
Alt Symbol	RNPU1Z, RPU1, SNRP70, Snp1, U1-70K, U170K, U1AP, U1RNP
Species	Human
Gene Type	protein-coding
Description	small nuclear ribonucleoprotein 70kDa (U1)
Other Description	U1 small nuclear ribonucleoprotein 70 kDa|U1 snRNP 70 kDa
Swissprots	B3KUA3 Q15687 P78494 Q9UE48 Q9UE47 Q15364 Q9UE45 P08621 P78493 Q9UFQ6 Q15689 Q99377 Q9UE46 Q15686
Accessions	AAA36571 AAA36572 AAA36573 EAW52445 EAW52446 EAW52447 EAW52448 EAW52449 EAW52450 EAW52451 EAW52452 EAW52453 P08621 AK027127 AK056808 BAG51812 AK096783 BAG53365 AK293120 BAF85809 AL117399 CAB55900 AL117507 CAB55969 AL560281 AL832819 BC000342 AAH00342 BC001315 AAH01315 BE397125 BM969999 CN292681 DA403443 DB031937 DB189176 M22636 AAA03001 X06811 CAA29960 X06812 CAA29961 X06813 CAA29962 X06814 CAA29963 X06815 CAA29964 X06816 CAA29965 X06817 CAA29966 X06818 CAA29967 X06819 X07401 CAA30303 X07402 CAA30304 X07403 CAA30305 X84841 CAA59278 XM_005259178 XP_005259235 XM_011527240 XP_011525542 XM_011527241 XP_011525543 NM_001009820 NM_001301069 NP_001287998 NM_003089 NP_003080
Function	Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
Subcellular Location	Nucleus. Nucleus speckle {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000250}. Note=Colocalizes with SCNM1 and LUC7L2 in nuclear speckles. {ECO:0000250}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SNRP70 protein fragment - ab132548 from Abcam Category Protein Source Wheat germ Species Human

Human SNRP70 protein fragment - ab70109 from Abcam Category Protein Source E. coli Species Human

SNRP70 peptide - ab95039 from Abcam Category Peptide

SNRP70 / SNRNP70 Antibody Blocking Peptide - LS-E4679 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SNRP70 / SNRNP70 Antibody Blocking Peptide - LS-E14667 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SNRP70 Protein - H00006625-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SNRNP70-Antibody-Center-Blocking-Peptide - BP17045c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human U1 small nuclear ribonucleoprotein 70 kDa (OPCA00481) - OPCA00481 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

SNRNP70 Protein (OPPA01355) - OPPA01355 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg

Human SNRP70 protein - orb246677 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

RNP protein - 30-1295 from Fitzgerald Category Protein Prices $1,195.00 Sizes 1 mg Source E.coli

SNRP70 Blocking Peptide - 33R-10176 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SNRP70 Blocking Peptide - 33R-7885 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SNRP70 Blocking Peptide - 33R-7148 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RNP U1 68k - P269-3 from Acris Antibodies Category Protein Prices $550.00 Sizes 100 µg Source E. coli Species Human

SNRNP70 - H00006625-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SNRNP70 - H00006625-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SNRNP70 - H00006625-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SNRNP70 - H00006625-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Small Nuclear Ribonucleoprotein 70kDa, Human Recombinant - 228-11579-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human U1snRNP-68 - 228-11579-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human U1snRNP-68 - 228-11579-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

Recombinant Human SNRNP70 protein - BP002060-PRO-445 from Syd Labs Category Protein Prices $160.00, $3,500.00 Sizes 20 µg, 1 mg Source E.coli-derived. Species Human

Recombinant Human SNRNP70, His-tagged - SNRNP70-227 from Creative Biomart Category Protein Source E.Coli.

SNRNP70 - RP-NKX-998 from Reagent Proteins Category Protein Prices $364.00, $3,668.00 Sizes 20.00 µg, 1 mg Source E. coli

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