SNRNP70

Gene Symbol SNRNP70
Entrez Gene 6625
Alt Symbol RNPU1Z, RPU1, SNRP70, Snp1, U1-70K, U170K, U1AP, U1RNP
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein 70kDa (U1)
Other Description U1 small nuclear ribonucleoprotein 70 kDa|U1 snRNP 70 kDa
Swissprots B3KUA3 Q15687 P78494 Q9UE48 Q9UE47 Q15364 Q9UE45 P08621 P78493 Q9UFQ6 Q15689 Q99377 Q9UE46 Q15686
Accessions AAA36571 AAA36572 AAA36573 EAW52445 EAW52446 EAW52447 EAW52448 EAW52449 EAW52450 EAW52451 EAW52452 EAW52453 P08621 AK027127 AK056808 BAG51812 AK096783 BAG53365 AK293120 BAF85809 AL117399 CAB55900 AL117507 CAB55969 AL560281 AL832819 BC000342 AAH00342 BC001315 AAH01315 BE397125 BM969999 CN292681 DA403443 DB031937 DB189176 M22636 AAA03001 X06811 CAA29960 X06812 CAA29961 X06813 CAA29962 X06814 CAA29963 X06815 CAA29964 X06816 CAA29965 X06817 CAA29966 X06818 CAA29967 X06819 X07401 CAA30303 X07402 CAA30304 X07403 CAA30305 X84841 CAA59278 XM_005259178 XP_005259235 XM_011527240 XP_011525542 XM_011527241 XP_011525543 NM_001009820 NM_001301069 NP_001287998 NM_003089 NP_003080
Function Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
Subcellular Location Nucleus. Nucleus speckle {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000250}. Note=Colocalizes with SCNM1 and LUC7L2 in nuclear speckles. {ECO:0000250}.
Top Pathways Spliceosome

U1 snRNP 70 (C-3) - sc-390899 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
U1 snRNP 70 (C-3): sc-390899. Western blot analysis of U1 snRNP 70 expression in HuT 78 (A) and Hep G2 (B) whole cell lysates.

U1 snRNP 70 (E-4) - sc-390988 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
U1 snRNP 70 (E-4): sc-390988. Western blot analysis of U1 snRNP 70 expression in Jurkat (A) and HuT 78 (B) whole cell lysates.

U1 snRNP 70 (C-18) - sc-9571 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
U1 snRNP 70 (C-18): sc-9571. Western blot analysis of U1 snRNP 70 expression in Jurkat (A) and HuT 78 (B) whole cell lysates.

U1 snRNP 70 (N-20) - sc-9569 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

U1 snRNP 70 (H-280) - sc-25371 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SNRP70 antibody - ab51266 from Abcam

Prices $400.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human pineal tissue labelling SNRP70 with ab51266 at 1/100. A Cy3 conjugated donkey anti-rabbit IgG (1/200) was used as teh secondary antibody. Positive staining shown in the nuclei of pinealocytes. Magnification: 20X. Exposure time: 0.5 - 2.0 seconds. Left - DAPI. Middle - SNRP70. Right - Merge.

Anti-SNRP70 antibody - ab83306 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SNRP70 antibody (ab83306) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 3 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLane 5 : Caco 2 (Human colonic carcinoma cell line) Whole Cell LysateLane 6 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 7 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-SNRP70 antibody - ab130715 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SNRP70 antibody (ab130715) at 1/100 dilution + CEM cell line lysates at 35 µgdeveloped using the ECL technique

Anti-SNRP70 / SNRNP70 Antibody - LS-C155148 from LifeSpan Bioscience

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRP70 / SNRNP70 Antibody (clone C4F4) - LS-C202655 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone C4F4

Anti-SNRP70 / SNRNP70 Antibody (clone 5BH5) - LS-C202654 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5BH5

Anti-SNRP70 / SNRNP70 Antibody (clone C4F4) - LS-C132782 from LifeSpan Bioscience

Prices $875.00
Sizes 100 µg
Host Human
Clonality Monoclonal
Clone C4F4

Anti-SNRP70 / SNRNP70 Antibody (aa195-223, AP) - LS-C269818 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRP70 / SNRNP70 Antibody (aa195-223, APC) - LS-C269819 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRP70 / SNRNP70 Antibody (aa195-223, Biotin) - LS-C269820 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRP70 / SNRNP70 Antibody (aa195-223, Azide-free, HRP) - LS-C269821 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRP70 / SNRNP70 Antibody (aa195-223, PE) - LS-C269823 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRP70 / SNRNP70 Antibody (aa195-223, FITC) - LS-C269822 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRP70 / SNRNP70 Antibody (aa301-350) - LS-C30305 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
B: HepG2 Cell Lysate

Anti-SNRP70 / SNRNP70 Antibody (aa195-223) - LS-C161350 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SNRNP70 Antibody western blot of CEM cell line lysates (35 ug/lane). The SNRNP70 antibody detected the SNRNP70 protein (arrow).

Anti-SNRP70 / SNRNP70 Antibody (aa194-223) - LS-C325237 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRP70 / SNRNP70 Antibody (aa21-70) - LS-C31633 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SNRNP70 / SNRP70 antibody LS-C31633 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-SNRP70 / SNRNP70 Antibody - LS-C334501 from LifeSpan Bioscience

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using SNRNP70 antibody.

Anti-SNRP70 / SNRNP70 Antibody (aa91-140) - LS-C30389 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SNRNP70 / SNRP70 antibody LS-C30389 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

SNRP70 Antibody - NBP1-57487 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SNRP70 Antibody [NBP1-57487] - Antibody Titration: 1 ug/ml HEK293.
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