| Gene Symbol |
HTR3B
|
| Entrez Gene |
9177
|
| Alt Symbol |
5-HT3B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
|
| Other Description |
5-HT3-B|5-hydroxytryptamine 3 receptor B subunit|5-hydroxytryptamine receptor 3B|serotonin-gated ion channel subunit
|
| Swissprots |
Q0VJC3 O95264 B0YJ23
|
| Accessions |
ACA06001 ACE96223 ACE96228 ACE96238 ACE96243 ACE96248 ACE96253 ACE96258 ACE96263 EAW67236 O95264 AF080582 AAD12242 AF169255 AAF03691 AK314268 BAG36930 AM293589 CAL25321 BC141515 AAI41516 XM_011543063 XP_011541365 XM_011543064 XP_011541366 XM_011543065 XP_011541367 XM_011543066 XP_011541368 NM_006028 NP_006019
|
| Function |
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. {ECO:0000269|PubMed:12867984}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:21138434}; Multi-pass membrane protein {ECO:0000269|PubMed:21138434}. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
|
| Tissue Specificity |
Expressed in the brain cortex, in the caudate nucleus, the hyppocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta. {ECO:0000269|PubMed:10521471, ECO:0000269|PubMed:9950429}.
|