Gene Symbol | HTR3B |
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Entrez Gene | 9177 |
Alt Symbol | 5-HT3B |
Species | Human |
Gene Type | protein-coding |
Description | 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic |
Other Description | 5-HT3-B|5-hydroxytryptamine 3 receptor B subunit|5-hydroxytryptamine receptor 3B|serotonin-gated ion channel subunit |
Swissprots | Q0VJC3 O95264 B0YJ23 |
Accessions | ACA06001 ACE96223 ACE96228 ACE96238 ACE96243 ACE96248 ACE96253 ACE96258 ACE96263 EAW67236 O95264 AF080582 AAD12242 AF169255 AAF03691 AK314268 BAG36930 AM293589 CAL25321 BC141515 AAI41516 XM_011543063 XP_011541365 XM_011543064 XP_011541366 XM_011543065 XP_011541367 XM_011543066 XP_011541368 NM_006028 NP_006019 |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. {ECO:0000269|PubMed:12867984}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:21138434}; Multi-pass membrane protein {ECO:0000269|PubMed:21138434}. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. |
Tissue Specificity | Expressed in the brain cortex, in the caudate nucleus, the hyppocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta. {ECO:0000269|PubMed:10521471, ECO:0000269|PubMed:9950429}. |
SR-3B (L-19) - sc-51193 from Santa Cruz Biotechnology
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SR-3B (H-71) - sc-99079 from Santa Cruz Biotechnology
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SR-3B (N-16) - sc-51195 from Santa Cruz Biotechnology
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SR-3B (Q-13) - sc-51196 from Santa Cruz Biotechnology
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Anti-5HT3B receptor antibody - ab39629 from Abcam
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Anti-5HT3B receptor antibody - ab71142 from Abcam
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Anti-5HT3B receptor antibody - ab90429 from Abcam
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Anti-HTR3B / 5-HT3B Receptor Antibody (Internal) - LS-C153361 from LifeSpan Bioscience
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Anti-HTR3B / 5-HT3B Receptor Antibody - LS-C308352 from LifeSpan Bioscience
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Anti-HTR3B / 5-HT3B Receptor Antibody (Internal) IHC-plus⢠- LS-B7535 from LifeSpan Bioscience
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Anti-HTR3B / 5-HT3B Receptor Antibody (aa378-391) - LS-C112848 from LifeSpan Bioscience
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Anti-HTR3B / 5-HT3B Receptor Antibody (aa187-200) - LS-C139783 from LifeSpan Bioscience
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Anti-HTR3B / 5-HT3B Receptor Antibody (N-Terminus) IHC-plus⢠- LS-B971 from LifeSpan Bioscience
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5-HT3B Antibody - NBP1-49591 from Novus Biologicals
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5-HT3B Antibody - NBP1-90316 from Novus Biologicals
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5-HT3B Antibody - NBP1-51969 from Novus Biologicals
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5HT3B receptor Polyclonal Antibody - bs-4289R from Bioss
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Anti-HTR3B antibody produced in goat - SAB2501285 from Sigma-Aldrich
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Anti-Htr3b antibody produced in goat - SAB2502002 from Sigma-Aldrich
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Anti-HTR3B antibody produced in rabbit - AV35186 from Sigma-Aldrich
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Anti-HTR3B antibody produced in rabbit - HPA039559 from Sigma-Aldrich
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Anti-HTR3B antibody produced in mouse - SAB1401455 from Sigma-Aldrich
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HTR3B antibody - N-terminal region (ARP35186_P050) - ARP35186_P050 from Aviva Systems Biology
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Serotonin-Receptor-3B--HTR3B-Antibody - AF1976a from Abgent, a WuXi AppTec company
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Goat Anti-Serotonin Receptor 3B / HTR3B Antibody (OAEB01375) - OAEB01375 from Aviva Systems Biology
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