SLIRP

Gene Symbol SLIRP
Entrez Gene 81892
Alt Symbol C14orf156, DC50, PD04872
Species Human
Gene Type protein-coding
Description SRA stem-loop interacting RNA binding protein
Other Description SRA stem-loop-interacting RNA-binding protein, mitochondrial
Swissprots J3KMY7 Q9GZT3
Accessions EAW81303 EAW81304 Q9GZT3 AF253980 AAG44629 AF271779 AAG44790 AJ272055 CAC81241 AY860853 AAX58600 BC017895 AAH17895 BM685909 BP289922 BQ083727 BU944910 BU955571 BU960115 EL951262 HQ257938 ADR82692 NM_001267863 NP_001254792 NM_001267864 NP_001254793 NM_031210 NP_112487 NR_052025
Function RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation. {ECO:0000269|PubMed:16762838}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:16762838}. Nucleus {ECO:0000269|PubMed:16762838}. Note=Predominantly mitochondrial. Some fraction is nuclear. In the nucleus, it is recruited to nuclear receptor target promoters.
Tissue Specificity Ubiquitously expressed, with highest level in heart, liver, skeletal muscle and testis. {ECO:0000269|PubMed:16762838}.

SLIRP / C14orf156 Antibody Blocking Peptide - LS-E15056 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SLIRP Blocking Peptide - NB110-37258PEP from Novus Biologicals

Category Peptide
Prices $69.00
Sizes 50 µg
Species Human

C14ORF156 Blocking Peptide - 33R-7071 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

C14orf156 fusion protein - Ag22945 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human SLIRP - SLIRP-974H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

SLIRP - TP305002 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
SLIRP

SLIRP Recombinant Protein Antigen - NBP1-85285PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

SLIRP Peptide, Human - M34GP14689H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

SRA stem-loop-interacting RNA-binding protein, mitochondrial (SLIRP), partial, Recombinant Protein - MBS1424991 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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