Gene Symbol | VKORC1L1 |
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Entrez Gene | 154807 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | vitamin K epoxide reductase complex, subunit 1-like 1 |
Other Description | VKORC1-like protein 1|vitamin K epoxide reductase complex subunit 1-like protein 1 |
Swissprots | Q6AHW9 E7ETM5 B4E222 Q8N0U8 Q6TEK6 |
Accessions | EAX07952 Q8N0U8 AK000750 AK001747 AK055860 AK124688 AK289522 BAF82211 AK304077 BAG64984 AL137548 AY423045 AAR82915 BC007465 BC014249 BC027734 AAH27734 BM991935 BX647631 CR627471 CAH10673 DQ572761 HQ447784 ADQ32268 XM_011515830 XP_011514132 XM_011515831 XP_011514133 NM_001284342 NP_001271271 NM_173517 NP_775788 |
Function | Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins. {ECO:0000269|PubMed:21367861, ECO:0000269|PubMed:23928358, ECO:0000269|PubMed:24532791}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21367861, ECO:0000269|PubMed:24532791}; Multi- pass membrane protein {ECO:0000269|PubMed:21367861, ECO:0000269|PubMed:24532791}. |
Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis |
VKORC1L1 (N-13) - sc-48710 from Santa Cruz Biotechnology
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VKORC1L1 (K-12) - sc-48709 from Santa Cruz Biotechnology
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VKORC1L1 (H-76) - sc-98893 from Santa Cruz Biotechnology
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VKORC1L1 (C-15) - sc-48708 from Santa Cruz Biotechnology
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Anti-VKORC1L1 antibody - ab116508 from Abcam
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Anti-VKORC1L1 antibody - C-terminal - ab136611 from Abcam
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Anti-VKORC1L1 Antibody (aa19-47, AP) - LS-C273342 from LifeSpan Bioscience
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Anti-VKORC1L1 Antibody (aa19-47, APC) - LS-C273343 from LifeSpan Bioscience
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Anti-VKORC1L1 Antibody (aa19-47, Biotin) - LS-C273344 from LifeSpan Bioscience
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Anti-VKORC1L1 Antibody (aa19-47, FITC) - LS-C273346 from LifeSpan Bioscience
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Anti-VKORC1L1 Antibody (aa19-47, Azide-free, HRP) - LS-C273347 from LifeSpan Bioscience
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Anti-VKORC1L1 Antibody (aa19-47, PE) - LS-C273348 from LifeSpan Bioscience
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Anti-VKORC1L1 Antibody (aa18-47) - LS-C326280 from LifeSpan Bioscience
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Anti-VKORC1L1 Antibody (C-Terminus) - LS-C169850 from LifeSpan Bioscience
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Anti-VKORC1L1 Antibody (aa19-47) - LS-C160532 from LifeSpan Bioscience
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VKORC1L1 Antibody - NBP2-13516 from Novus Biologicals
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ANTI-VKORC1L1 (N-TERM) antibody produced in rabbit - SAB1302139 from Sigma-Aldrich
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Anti-VKORC1L1 antibody produced in rabbit - HPA053954 from Sigma-Aldrich
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VKORC1L1 Antibody - C-terminal region (ARP66985_P050) - ARP66985_P050 from Aviva Systems Biology
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VKORC1L1-Antibody-N-term - AP13669a from Abgent, a WuXi AppTec company
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VKORC1L1 Antibody - N-terminal region (OAAB09969) - OAAB09969 from Aviva Systems Biology
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VKORC1L1 Antibody - abx027528 from Abbexa
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Rabbit Anti-Human VKORC1L1 (N-term) - 102-12092 from RayBiotech
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VKORC1L1 antibody (N-term) - STJ43319 from St John's Laboratory Ltd
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Anti-VKORC1L1 (aa 127-176) polyclonal antibody - DPABH-26849 from Creative Diagnostics
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