Gene Symbol |
CHRNB1
|
Entrez Gene |
1140
|
Alt Symbol |
ACHRB, CHRNB, CMS1D, CMS2A, SCCMS
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cholinergic receptor, nicotinic, beta 1 (muscle)
|
Other Description |
acetylcholine receptor subunit beta|acetylcholine receptor, nicotinic, beta 1 (muscle)|cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
|
Swissprots |
P11230 B7Z5H1 Q96FB8 Q8IZ46
|
Accessions |
EAW90186 P11230 AK294880 BAH11912 AK298938 BAH12907 AK308106 BC011371 AAH11371 BC023553 AAH23553 DQ894641 ABM85567 X14830 CAA32939 NM_000747 NP_000738
|
Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
Neuroactive ligand-receptor interaction
|