CHRNB1

Gene Symbol CHRNB1
Entrez Gene 1140
Alt Symbol ACHRB, CHRNB, CMS1D, CMS2A, SCCMS
Species Human
Gene Type protein-coding
Description cholinergic receptor, nicotinic, beta 1 (muscle)
Other Description acetylcholine receptor subunit beta|acetylcholine receptor, nicotinic, beta 1 (muscle)|cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
Swissprots P11230 B7Z5H1 Q96FB8 Q8IZ46
Accessions EAW90186 P11230 AK294880 BAH11912 AK298938 BAH12907 AK308106 BC011371 AAH11371 BC023553 AAH23553 DQ894641 ABM85567 X14830 CAA32939 NM_000747 NP_000738
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Top Pathways Neuroactive ligand-receptor interaction

AChRβ (B3) - sc-58600 from Santa Cruz Biotechnology

Prices $279.00
Sizes 250 µl ascites
Host Mouse
Clonality Monoclonal
AChRβ (B3): sc-58600. Western blot analysis of AChRβ expression in human AChRβ transfected: sc-111175 (A) and non-transfected: sc-110760 (B) 293 whole cell lysates.

AChRβ1 (A-2) - sc-166567 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AChRβ1 (A-2): sc-166567. Western blot analysis of AChRβ1 expression in non-transfected: sc-110760 (A) and human AChRβ1 transfected: sc-111175 (B) 293 whole cell lysates.

AChRβ1 (73) - sc-58598 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
AChRβ1 (73): sc-58598. Western blot analysis of AChRβ1 expression in non-transfected: sc-110760 (A) and human AChRβ1 transfected: sc-111175 (B) 293 whole cell lysates.

AChRβ1 (C-20) - sc-1448 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AChRβ1 (C-20): sc-1448. Western blot analysis of nicotinic acetylcholine receptor β1 subunit expression in mouse heart (A) and rat brain (B) extracts and PC-12 (C) whole cell lysate.

AChRβ1 (E-2) - sc-166032 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AChRβ1 (E-2): sc-166032. Western blot analysis of AChRβ1 expression in non-transfected: sc-110760 (A) and human AChRβ1 transfected: sc-111175 (B) 293 whole cell lysates.

AChRβ1 (H-101) - sc-11371 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AChRβ1 (H-101): sc-11371. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse brain tissue showing membrane localization.

AChRβ1 (123) - sc-65790 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
AChRβ1 (123): sc-65790. Western blot analysis of AChRβ1 expression in non-transfected 293T: sc-117752 (A), human AChRβ1 transfected 293T: sc-171924 (B) and IMR-32 (C) whole cell lysates.

p-AchRβ1 (Tyr 390) - sc-17087 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Nicotinic Acetylcholine Receptor beta antibody - ab66429 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Nicotinic Acetylcholine Receptor beta antibody - ab110486 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Nicotinic Acetylcholine Receptor beta antibody (ab110486) at 1/500 dilution + HeLa cell lysate

Anti-Nicotinic Acetylcholine Receptor beta antibody - ab177075 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Nicotinic Acetylcholine Receptor beta antibody (ab177075) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : MCF7 cell lysate

Anti-Nicotinic Acetylcholine Receptor beta antibody [B3] - ab11150 from Abcam

Prices $359.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Clone B3

Anti-Nicotinic Acetylcholine Receptor beta antibody [EP2067Y] - ab76159 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP2067Y
Overlay histogram showing SHSY-5Y cells stained with ab76159 (red line). The cells were fixed with 80% methanol (5 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab76159, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive result in 4% paraformaldehyde (10 min) fixed SHSY-5Y cells used under the same conditions. Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Anti-CHRNB1 Antibody - LS-C155371 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded H661 xenograft, using Nicotinic Acetylcholine Receptor beta antibody at 1:250 dilution.

Anti-CHRNB1 Antibody - LS-C34794 from LifeSpan Bioscience

Prices $465.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal

Anti-CHRNB1 Antibody - LS-C91102 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal

Anti-CHRNB1 Antibody (C-Terminus) - LS-C144760 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB1 Antibody (C-Terminus) - LS-C153365 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNB1 Antibody (clone 23630) - LS-C195349 from LifeSpan Bioscience

Prices $215.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 23630

Anti-CHRNB1 Antibody (clone 4G4) - LS-C196916 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4G4

Anti-CHRNB1 Antibody - LS-C341564 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNB1 Antibody (Internal, clone EPR2068) - LS-C105535 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2068
Western blot analysis on (A) fetal brain, (B) fetal thymus, (C) skeletal muscle and (D) heart lysates using anti-ACHR-beta antibody (LS-C105535).

Anti-CHRNB1 Antibody (Extracellular, clone EP2067Y) - LS-C50072 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP2067Y
Western blot analysis on human brain lysate using anti-ACHR-beta antibody, dilution 1:1000.

Anti-CHRNB1 Antibody (N-Terminus) - LS-C345381 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of ACHB Antibody with human 721_B Whole Cell lysate.

Anti-CHRNB1 Antibody - LS-C333961 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human kidney cancer using CHRNB1 antibody at dilution of 1:200 (x400 lens)
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