Gene Symbol | CHRNB1 |
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Entrez Gene | 1140 |
Alt Symbol | ACHRB, CHRNB, CMS1D, CMS2A, SCCMS |
Species | Human |
Gene Type | protein-coding |
Description | cholinergic receptor, nicotinic, beta 1 (muscle) |
Other Description | acetylcholine receptor subunit beta|acetylcholine receptor, nicotinic, beta 1 (muscle)|cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) |
Swissprots | P11230 B7Z5H1 Q96FB8 Q8IZ46 |
Accessions | EAW90186 P11230 AK294880 BAH11912 AK298938 BAH12907 AK308106 BC011371 AAH11371 BC023553 AAH23553 DQ894641 ABM85567 X14830 CAA32939 NM_000747 NP_000738 |
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |
AChRβ1 siRNA (h) - sc-29630 from Santa Cruz Biotechnology
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AChRβ1 shRNA Plasmid (h) - sc-29630-SH from Santa Cruz Biotechnology
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AChRβ1 shRNA (h) Lentiviral Particles - sc-29630-V from Santa Cruz Biotechnology
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Nicotinic Acetylcholine Receptor beta RNAi - H00001140-R01 from Novus Biologicals
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MISSION® esiRNA - EHU153371 from Sigma-Aldrich
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MISSION® esiRNA - EHU098991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1794 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1794 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06922 from Sigma-Aldrich
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CHRNB1 siRNA (Human) - CRH0817 from Cohesion Biosciences
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CHRNB1 - MBS8222750 from MyBioSource
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shRNA set against Human CHRNB1 (NM_000747.2) - SHH263621 from Creative biogene
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shRNA set against Human CHRNB1(NM_000747.2) - SHG177391 from Creative biogene
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CHRNB1 shRNA Plasmid (Human) - CHH0817 from Cohesion Biosciences
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CHRNB1 miRNA 3'UTR clone - MiUTR1H-02147 from Creative biogene
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