RELB

Gene Symbol	RELB
Entrez Gene	5971
Alt Symbol	I-REL, IREL, REL-B
Species	Human
Gene Type	protein-coding
Description	v-rel avian reticuloendotheliosis viral oncogene homolog B
Other Description	transcription factor RelB|v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)|v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Swissprots	Q6GTX7 Q9UEI7 Q01201
Accessions	AAC82346 ABC40746 EAW57316 Q01201 AK290594 BAF83283 AL583128 AW137991 BC028013 AAH28013 BI906507 BM684710 DA940587 M83221 AAA36127 XM_005259127 XP_005259184 XM_005259128 XP_005259185 NM_006509 NP_006500
Function	NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF- kappa-B inhibitor (I-kappa-
Subcellular Location	Nucleus {ECO:0000269|PubMed:20873783}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20873783}. Note=Colocalizes with NEK6 in the centrosome.
Top Pathways	MAPK signaling pathway, Osteoclast differentiation, HTLV-I infection, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human Phospho-RELB (Ser552) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1614 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human RELB ELISA Kit (Cell-Based ELISA) - LS-F2284 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Human RELB ELISA Kit (Sandwich ELISA) - LS-F7395 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Rabbit anti-RelB Antibody, Affinity Purified - PLA0244 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

V-Rel Reticuloendotheliosis Viral Oncogene Homolog B, RELB, Human, ELISA Kit - E-EL-H2425 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Transcription factor RelB (RELB), Human, ELISA Kit - E01T0640 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Transcription factor RelB, RELB, Human, ELISA Kit - E1732h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/ml

V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB), Human, ELISA Kit - SEB826Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.062ng/mL Range 0.156-10ng/mL

V-Rel Reticuloendotheliosis Viral Oncogene Homolog B, RELB, Mouse, ELISA Kit - E-EL-M1183 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

V-Rel Reticuloendotheliosis Viral Oncogene Homolog B, RELB, Rabbit, ELISA Kit - E-EL-RB1642 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

V-Rel Reticuloendotheliosis Viral Oncogene Homolog B, RELB, Chicken, ELISA Kit - E-EL-Ch1985 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

V-Rel Reticuloendotheliosis Viral Oncogene Homolog B, RELB, Porcine, ELISA Kit - E-EL-P2161 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

V-Rel Reticuloendotheliosis Viral Oncogene Homolog B, RELB, Monkey, ELISA Kit - E-EL-MK1400 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human RELB ELISA Kit - HR0357 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine RELB ELISA Kit - AR0357 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

RelB Colorimetric Cell-Based ELISA Kit - CB5604 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

RelB (Phospho-Ser573) Colorimetric Cell-Based ELISA Kit - CBP1669 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Human RELB(V-Rel Reticuloendotheliosis Viral Oncogene Homolog B) ELISA Kit - E-EL-H2425 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B) CLIA Kit - E-CL-H1426 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

RELB, ELISA Kit - MBS2511941 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156--10ng/mL

Transcription factor RelB (RELB), ELISA Kit - MBS7203846 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor RelB (RELB), ELISA Kit - MBS7234345 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor RelB (RELB), ELISA Kit - MBS7226516 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor RelB (RELB), ELISA Kit - MBS7203479 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor RelB (RELB), ELISA Kit - MBS7246498 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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