RELB

Gene Symbol	RELB
Entrez Gene	5971
Alt Symbol	I-REL, IREL, REL-B
Species	Human
Gene Type	protein-coding
Description	v-rel avian reticuloendotheliosis viral oncogene homolog B
Other Description	transcription factor RelB|v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)|v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Swissprots	Q6GTX7 Q9UEI7 Q01201
Accessions	AAC82346 ABC40746 EAW57316 Q01201 AK290594 BAF83283 AL583128 AW137991 BC028013 AAH28013 BI906507 BM684710 DA940587 M83221 AAA36127 XM_005259127 XP_005259184 XM_005259128 XP_005259185 NM_006509 NP_006500
Function	NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF- kappa-B inhibitor (I-kappa-
Subcellular Location	Nucleus {ECO:0000269|PubMed:20873783}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20873783}. Note=Colocalizes with NEK6 in the centrosome.
Top Pathways	MAPK signaling pathway, Osteoclast differentiation, HTLV-I infection, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Rel B full length protein - ab152653 from Abcam Category Protein Source Wheat germ Species Human

Human Rel B full length protein - ab84654 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

RELB Antibody Blocking Peptide - LS-E10839 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RELB Antibody Blocking Peptide - LS-E16039 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RELB Antibody Blocking Peptide - LS-E13255 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RELB Antibody Blocking Peptide - LS-E13256 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RELB Antibody Blocking Peptide - LS-E13979 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RELB Antibody Blocking Peptide - LS-E13978 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RELB Antibody Blocking Peptide - LS-E13588 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RelB Recombinant Protein - H00005971-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

RELB Protein Lysate (APL10324) - APL10324 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

RELB Protein Lysate (APL10325) - APL10325 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

RELB Blocking Peptide - 33R-3469 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RELB Blocking Peptide - 33R-6307 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RELB Blocking Peptide - 33R-2979 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human RELB Protein - abx069697 from Abbexa Category Protein Source E.coli Species Human

RELB / I-Rel - H00005971-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RELB / I-Rel - H00005971-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB), Human - 20-8062 from ARP American Research Products Category Protein Prices $469.00 Sizes 50 µg Source E.coli Species Human

RELB fusion protein - ag13824 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

RelB (Phospho-Ser552) Antibody Blocking Peptide - GWB-C321F6 from Genway Biotech Category Peptide Prices $138.00 Sizes 100 µg

Recombinant Human RELB, His-tagged - RELB-1487H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus.

Recombinant Human RELB, His-tagged - RELB-30492TH from Creative Biomart Category Protein

Recombinant V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) - RPB826Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) - RPB826Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

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