AMICA1

Gene Symbol AMICA1
Entrez Gene 120425
Alt Symbol AMICA, CREA7-1, CREA7-4, Gm638, JAML
Species Human
Gene Type protein-coding
Description adhesion molecule, interacts with CXADR antigen 1
Other Description adhesion molecule AMICA|adhesion molecule interacting with CXADR antigen 1|dendritic-cell specific protein CREA7-1|dendritic-cell specific protein CREA7-4|junctional adhesion molecule-like
Swissprots Q8NF70 Q5DTC6 B0YIV1 Q8N9I7 B0YIV2 Q7Z499 Q496M1 Q86YT9
Accessions ACA05929 ACA05930 CCF77025 CCF77026 EAW67354 EAW67355 Q86YT9 AJ515553 CAD56620 AK057590 AK090409 BAC03390 AK094399 BAC04347 AK097285 BAG53445 AK298722 BAG60876 AK300851 BAG62502 AK301099 BAG62698 AW804077 AY093686 AAM15730 AY093687 AAM15731 AY138965 AAN52117 AY358362 AAQ88728 BC100794 AAI00795 BC100795 AAI00796 BC100796 AAI00797 BC100797 AAI00798 DA090367 DC296115 XM_005271407 XP_005271464 XM_011542606 XP_011540908 XM_011542607 XP_011540909 NM_001098526 NP_001091996 NM_001286570 NP_001273499 NM_001286571 NP_001273500 NM_153206 NP_694938 NR_104479
Function Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T- cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T- cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR. {ECO:0000269|PubMed:12869515, ECO:0000269|PubMed:15800062, ECO:0000269|PubMed:18948633, ECO:0000269|PubMed:19064666}.
Subcellular Location Cell membrane; Single-pass type I membrane protein. Cell junction. Note=Localized at the plasma membrane and enriched in areas of cell-cell contacts.
Tissue Specificity Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus. Preferentially expressed by mature leukocytes (at protein level). {ECO:0000269|PubMed:12869515, ECO:0000269|PubMed:18948633, ECO:0000269|PubMed:19064666}.

Human AMICA / JAML ELISA Kit (Custom ELISA) - LS-F332 from LifeSpan Bioscience

Category ELISA Kit
Prices $670.00, $1,190.00, $2,570.00
Sizes 1 plate, 2 plate, 5 plate
Sensitivity To be determined
Range To be determined

Human AMICA1 / Junctional Adhesion Molecule-like ELISA Kit - RAB0604 from Sigma-Aldrich

Category ELISA Kit
Prices $633.00
Sizes 1 kt

Human AMICA DuoSet ELISA - DY3449 from R&D Systems

Category ELISA Kit
Prices $649.00
Sizes 1 kit (for 15 Plates)
Range 234.00 - 15,000 pg/mL

Custom Human AMICA ELISA - ELH-AMICA from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

adhesion molecule, interacts with CXADR antigen 1, ELISA Kit - MBS9320977 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/ml.
Range 3.12 ng/ml - 100 ng/ml.

Human JAML / AMICA ELISA Pair Set - SEK10120-5 from Sino Biological

Category ELISA Kit
Prices $350.00, $350.00
Sizes 5 plates, 15 plates

Human JAML / AMICA ELISA Kit - NS-E10254 from Novatein Biosciences

Category ELISA Kit
Prices $459.00
Sizes 96 t
Sensitivity 200 pg/mL
Range 234 - 30000 pg/ml

Human AMICA ELISA kit - orb79190 from Biorbyt

Category ELISA Kit
Prices $884.00, $1,513.00, $3,239.00
Sizes 96 well, 192 assays, 480 assays

Human AMICA ELISA Kit - NR-E10061 from Novatein Biosciences

Category ELISA Kit
Prices $532.50, $1,049.50, $1,878.90
Sizes 1x96t, 2x96t, 4x96t
Range 234-15000pg/ml

Human AMICA ELISA - ELH-AMICA-1 from RayBiotech

Category ELISA Kit
Prices $471.00, $847.80, $1,884.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human JAML ELISA Kit - E087094 from Biobool

Category ELISA Kit

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9368181 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9368270 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9362536 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9344154 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9344394 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9345348 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9345353 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9369204 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9345131 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9357302 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9355049 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9369774 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9366433 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit - MBS9356863 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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