Gene Symbol | HIST2H2BF |
---|---|
Entrez Gene | 440689 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 2, H2bf |
Other Description | histone H2B type 2-F |
Swissprots | A8K0U9 Q5QNW6 B4DLA9 |
Accessions | CAI12558 Q5QNW6 AK092418 BAC03883 AK289664 BAF82353 AK296916 BAG59471 AK299108 BAG61164 BC110793 AAI10794 DA042901 XM_006711335 XP_006711398 XM_006711336 XP_006711399 XM_006711337 XP_006711400 NM_001024599 NP_001019770 NM_001161334 NP_001154806 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
histone cluster 2, H2bf, ELISA Kit - MBS9335442 from MyBioSource
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Human HIST2H2BF ELISA Kit - E018781 from Biobool
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