| Gene Symbol | HIST2H2BF |
|---|---|
| Entrez Gene | 440689 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | histone cluster 2, H2bf |
| Other Description | histone H2B type 2-F |
| Swissprots | A8K0U9 Q5QNW6 B4DLA9 |
| Accessions | CAI12558 Q5QNW6 AK092418 BAC03883 AK289664 BAF82353 AK296916 BAG59471 AK299108 BAG61164 BC110793 AAI10794 DA042901 XM_006711335 XP_006711398 XM_006711336 XP_006711399 XM_006711337 XP_006711400 NM_001024599 NP_001019770 NM_001161334 NP_001154806 |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Subcellular Location | Nucleus. Chromosome. |
| Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
HIST2H2BF cDNA (ANA11492) - ANA11492 from Aviva Systems Biology
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Human HIST2H2BF ORF clone(NM_001024599.3) - CDCR005563 from Creative biogene
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Mouse HIST2H2BF ORF clone (NM_001161334.1) - CDCL117371 from Creative biogene
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Human HIST2H2BF cDNA Clone(NM_001161334.1) - CDFH008546 from Creative biogene
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