Gene Symbol | ABCB11 |
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Entrez Gene | 8647 |
Alt Symbol | ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
Other Description | ABC member 16, MDR/TAP subfamily|ATP-binding cassette sub-family B member 11|bile salt export pump|progressive familial intrahepatic cholestasis 2|sister p-glycoprotein |
Swissprots | O95342 Q9UNB2 Q53TL2 |
Accessions | AAY24100 AAY24305 CAI54162 CAI54163 EAX11285 EAX11286 EAX11287 O95342 AB012959 BAA88711 AF091582 AAC77455 AF136523 AAD28285 AK302540 BAG63812 AK303050 BAG64170 XM_006712817 XP_006712880 XM_011512077 XP_011510379 XM_011512078 XP_011510380 XM_011512079 XP_011510381 XM_011512080 XP_011510382 XM_011512081 XP_011510383 NM_003742 NP_003733 |
Function | Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ. |
Top Pathways | ABC transporters, Bile secretion |
BSEP (P-18) - sc-17294 from Santa Cruz Biotechnology
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BSEP (N-16) - sc-17292 from Santa Cruz Biotechnology
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BSEP (H-180) - sc-25571 from Santa Cruz Biotechnology
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BSEP (F-6) - sc-74500 from Santa Cruz Biotechnology
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Anti-ABCB11 antibody - ab112494 from Abcam
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Anti-ABCB11 antibody - ab155421 from Abcam
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Anti-ABCB11 antibody [EP8790] - ab140616 from Abcam
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Anti-ABCB11 antibody - Carboxyterminal end - ab71793 from Abcam
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Anti-ABCB11 / BSEP Antibody (aa420-656) - LS-C314966 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa1038-1067) - LS-C100358 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa1299-1313) - LS-C312556 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa705-718) IHC-plus⢠- LS-B2170 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa1053-1067) - LS-C2973 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa1038-1067, AP) - LS-C243849 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa1038-1067, PE) - LS-C243854 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa1038-1067, FITC) - LS-C243850 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa1038-1067, APC) - LS-C243847 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa1038-1067, Biotin) - LS-C243848 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa1038-1067, Azide-free, HRP) - LS-C247472 from LifeSpan Bioscience
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Anti-ABCB11 / BSEP Antibody (aa1045-1075) - LS-C326969 from LifeSpan Bioscience
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ABCB11 Antibody - NBP1-31824 from Novus Biologicals
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ABCB11 Antibody - NBP1-89319 from Novus Biologicals
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Monoclonal Anti-MDR3 P-Glycoprotein antibody produced in mouse - M7317 from Sigma-Aldrich
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Anti-ABCB11 antibody produced in rabbit - HPA019035 from Sigma-Aldrich
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ABCB11-Antibody-C-term - AP6110a from Abgent, a WuXi AppTec company
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