Gene Symbol | ABCB11 |
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Entrez Gene | 8647 |
Alt Symbol | ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
Other Description | ABC member 16, MDR/TAP subfamily|ATP-binding cassette sub-family B member 11|bile salt export pump|progressive familial intrahepatic cholestasis 2|sister p-glycoprotein |
Swissprots | O95342 Q9UNB2 Q53TL2 |
Accessions | AAY24100 AAY24305 CAI54162 CAI54163 EAX11285 EAX11286 EAX11287 O95342 AB012959 BAA88711 AF091582 AAC77455 AF136523 AAD28285 AK302540 BAG63812 AK303050 BAG64170 XM_006712817 XP_006712880 XM_011512077 XP_011510379 XM_011512078 XP_011510380 XM_011512079 XP_011510381 XM_011512080 XP_011510382 XM_011512081 XP_011510383 NM_003742 NP_003733 |
Function | Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ. |
Top Pathways | ABC transporters, Bile secretion |
ABCB11 / BSEP Blocking Peptide - LS-E16055 from LifeSpan Bioscience
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ABCB11 / BSEP Antibody Blocking Peptide - LS-E8078 from LifeSpan Bioscience
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ABCB11-Antibody-C-term-Blocking-Peptide - BP6110a from Abgent, a WuXi AppTec company
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ABCB11 Blocking Peptide - 33R-8751 from Fitzgerald
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Recombinant Human ABCB11 - ABCB11-2532H from Creative Biomart
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Recombinant ATP Binding Cassette Transporter B11 (ABCB11) - RPD641Mu01 from Uscn Life Science Inc.
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ABCB11 Protein - abx163331 from Abbexa
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Recombinant ATP Binding Cassette Transporter B11 (ABCB11) - RPD641Hu01 from Uscn Life Science Inc.
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Recombinant ATP Binding Cassette Transporter B11 (ABCB11) - RPD641Hu01 from Cloud-clone
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ABCB11 Recombinant Protein Antigen - NBP1-89319PEP from Novus Biologicals
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ABCB11-Blocking-Peptide-C-term - BP21646b from Abgent, a WuXi AppTec company
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ABCB11 Peptide, Human - M34GP00042H from Creative Peptides
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ABCB11 Recombinant Protein (OPCD00746) - OPCD00746 from Aviva Systems Biology
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Bile salt export pump (ABCB11), partial, Recombinant Protein - MBS1019641 from MyBioSource
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Recombinant Human ABCB11 protein, His & T7-tagged - ABCB11-8135H from Creative Biomart
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