KCNE3

Gene Symbol KCNE3
Entrez Gene 10008
Alt Symbol HOKPP, HYPP, MiRP2
Species Human
Gene Type protein-coding
Description potassium channel, voltage gated subfamily E regulatory beta subunit 3
Other Description cardiac voltage-gated potassium channel accessory subunit|minK-related peptide 2|minimum potassium ion channel-related peptide 2|potassium channel subunit beta MiRP2|potassium voltage-gated channel subfamily E member 3|potassium voltage-gated channel, Isk-related family, member 3|voltage-gated K+ channel subunit MIRP2
Swissprots Q9Y6H6
Accessions ABQ01240 EAW74938 Q9Y6H6 AF076531 AAD28089 AF302494 AAG16255 AK311876 BAG34817 BC032235 BC110612 AAI10613 BC113743 AAI13744 BM757131 CD709836 CK301015 CR457209 CAG33490 CR936625 CAI56768 DQ192291 ABB00304 DQ192292 ABB00305 DQ891015 ABM81941 DR006135 XM_011544713 XP_011543015 NM_005472 NP_005463
Function Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Widely expressed with highest levels in kidney and moderate levels in small intestine. {ECO:0000269|PubMed:10646604}.
Top Pathways Protein digestion and absorption

KCNE3 (G-6) - sc-393841 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KCNE3 (G-6): sc-393841. Western blot analysis of KCNE3 expression in HeLa whole cell lysate.

KCNE3 (H-80) - sc-28796 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
KCNE3 (H-80): sc-28796. Western blot analysis of human recombinant KCNE3 fusion protein.

KCNE3 (L-20) - sc-10648 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

KCNE3 (N-18) - sc-10647 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KCNE3 (N-18): sc-10647. Western blot analysis of KCNE3 expression in HeLa whole cell lysate.

Anti-KCNE3 antibody - ab86203 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-KCNE3 antibody - ab136659 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labelling KCNE3 with ab136659 at 3.75µg/ml after heat-induced antigen retrieval.

Anti-KCNE3 antibody - ab189022 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of formalin-fixed, paraffin-embedded human kidney tissue labelling KCNE3 with ab189022 at 5 µg/ml.

Anti-KCNE3 Antibody (aa39-51) IHC-plus™ - LS-B7398 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-KCNE3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7398 concentration 3.75 ug/ml.

Anti-KCNE3 Antibody (Internal) IHC-plus™ - LS-A9563 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-KCNE3 antibody LS-A9563 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-KCNE3 Antibody (Internal) IHC-plus™ - LS-A9564 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-KCNE3 antibody LS-A9564 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MiRP2 Antibody - NBP1-30638 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MiRP2 Antibody - NBP1-49885 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

MiRP2 Antibody - NBP1-83238 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: MiRP2 Antibody [NBP1-83238] - Staining of human kidney shows strong cytoplasmic positivity in granular pattern in tubular cells.

KCNE3 Polyclonal Antibody - bs-11661R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Paraformaldehyde-fixed, paraffin embedded rat kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with KCNE3 Polyclonal Antibody, Unconjugated (bs-11661R) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.

KCNE3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11661R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNE3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11661R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNE3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11661R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNE3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11661R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNE3 Polyclonal Antibody, Cy3 Conjugated - bs-11661R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNE3 Polyclonal Antibody, Cy5 Conjugated - bs-11661R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNE3 Polyclonal Antibody, Cy5.5 Conjugated - bs-11661R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNE3 Polyclonal Antibody, Cy7 Conjugated - bs-11661R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNE3 Polyclonal Antibody, FITC Conjugated - bs-11661R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNE3 Polyclonal Antibody, Biotin Conjugated - bs-11661R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNE3 Polyclonal Antibody, HRP Conjugated - bs-11661R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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