KCNE3
| Gene Symbol | KCNE3 |
|---|---|
| Entrez Gene | 10008 |
| Alt Symbol | HOKPP, HYPP, MiRP2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | potassium channel, voltage gated subfamily E regulatory beta subunit 3 |
| Other Description | cardiac voltage-gated potassium channel accessory subunit|minK-related peptide 2|minimum potassium ion channel-related peptide 2|potassium channel subunit beta MiRP2|potassium voltage-gated channel subfamily E member 3|potassium voltage-gated channel, Isk-related family, member 3|voltage-gated K+ channel subunit MIRP2 |
| Swissprots | Q9Y6H6 |
| Accessions | ABQ01240 EAW74938 Q9Y6H6 AF076531 AAD28089 AF302494 AAG16255 AK311876 BAG34817 BC032235 BC110612 AAI10613 BC113743 AAI13744 BM757131 CD709836 CK301015 CR457209 CAG33490 CR936625 CAI56768 DQ192291 ABB00304 DQ192292 ABB00305 DQ891015 ABM81941 DR006135 XM_011544713 XP_011543015 NM_005472 NP_005463 |
| Function | Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Widely expressed with highest levels in kidney and moderate levels in small intestine. {ECO:0000269|PubMed:10646604}. |
| Top Pathways | Protein digestion and absorption |
KCNE3 Antibody Blocking Peptide - LS-E27244 from LifeSpan Bioscience
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KCNE3 Antibody Blocking Peptide - LS-E29688 from LifeSpan Bioscience
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KCNE3 Antibody Blocking Peptide - LS-E29687 from LifeSpan Bioscience
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KCNE3 blocking peptide - GTX88130-PEP from GeneTex
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KCNE3 Peptide - AC21-2066-P from Abcore
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KCNE3 Peptide - 42-497P from ProSci
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KCNE3 fusion protein - Ag4145 from Proteintech Group
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Recombinant Human KCNE3, GST-tagged - KCNE3-241H from Creative Biomart
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Recombinant Human KCNE3 - KCNE3-697H from Creative Biomart
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KCNE3, Peptide - MBS427256 from MyBioSource
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MiRP2 Recombinant Protein Antigen - NBP1-83238PEP from Novus Biologicals
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KCNE3 Peptide, Human - M34GP07942H from Creative Peptides
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