Gene Symbol | RBM38 |
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Entrez Gene | 55544 |
Alt Symbol | HSRNASEB, RNPC1, SEB4B, SEB4D, dJ800J21.2 |
Species | Human |
Gene Type | protein-coding |
Description | RNA binding motif protein 38 |
Other Description | CLL-associated antigen KW-5|RNA-binding protein 38|RNA-binding region (RNP1, RRM) containing 1|RNA-binding region-containing protein 1|ssDNA-binding protein SEB4 |
Swissprots | Q9BYK4 Q9BYK3 A6NMU6 A6NDK1 Q15350 Q9H0Z9 Q15351 |
Accessions | EAW75520 EAW75521 EAW75522 Q9H0Z9 AF432218 AAL99924 BC018711 AAH18711 BE840212 BF371746 BM549757 DB504051 DN998561 DQ891994 ABM82920 DQ895184 ABM86110 X75314 CAA53063 XM_005260446 XP_005260503 XM_011528885 XP_011527187 NM_001291780 NP_001278709 NM_017495 NP_059965 NM_183425 NP_906270 |
Function | RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2- IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation. {ECO:0000269|PubMed:17050675, ECO:0000269|PubMed:19285943}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:17050675}. Nucleus {ECO:0000269|PubMed:17050675}. |
Human RBM38 full length protein - ab163121 from Abcam
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RBM38 Antibody Blocking Peptide - LS-E14982 from LifeSpan Bioscience
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RBM38 Antibody Blocking Peptide - LS-E14981 from LifeSpan Bioscience
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Recombinant Human RNPC1 Protein - H00055544-P01 from Novus Biologicals
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RBM38 Blocking Peptide - 33R-7794 from Fitzgerald
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RBM38 Blocking Peptide - 33R-5295 from Fitzgerald
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RBM38 - H00055544-P01 from Acris Antibodies
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RBM38 fusion protein - Ag9911 from Proteintech Group
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RBM38 fusion protein - ag9748 from Proteintech Group
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Recombinant Human RBM38, His-tagged - RBM38-2215H from Creative Biomart
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Recombinant Human RBM38 - RBM38-1141H from Creative Biomart
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Recombinant RNA Binding Motif Protein 38 (RBM38) - RPG647Hu01 from Uscn Life Science Inc.
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Recombinant RNA Binding Motif Protein 38 (RBM38) - RPG647Hu01 from Cloud-clone
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Recombinant Human RNA-binding protein 38(RBM38) - CSB-YP880939HU CSB-EP880939HU CSB-BP880939HU CSB-MP880939HU from Cusabio
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RBM38 (transcript variant 2) - TP311451 from Acris Antibodies
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RBM38 Peptide, Human - M34GP13063H from Creative Peptides
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RBM38 Recombinant Protein (OPCD06613) - OPCD06613 from Aviva Systems Biology
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RNA-binding protein 38 (RBM38), Recombinant Protein - MBS1373745 from MyBioSource
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