Gene Symbol |
EDC3
|
Entrez Gene |
80153
|
Alt Symbol |
LSM16, YJDC, YJEFN2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
enhancer of mRNA decapping 3
|
Other Description |
LSM16 homolog (EDC3, S. cerevisiae)|enhancer of mRNA decapping 3 homolog|enhancer of mRNA-decapping protein 3|hYjeF_N2|hYjeF_N2-15q23|yjeF N-terminal domain-containing protein 2|yjeF domain containing|yjeF domain-containing protein 1|yjeF_N2
|
Swissprots |
Q9H797 D3DW61 Q96F86 B3KPH0
|
Accessions |
EAW99316 EAW99317 EAW99318 EAW99319 Q96F86 AF193058 AAG22486 AK024781 BAB15001 AK056339 BAG51682 AK225099 AL133447 BC011534 AAH11534 BC021271 AAH21271 BM999594 CA440205 DA168050 DB007958 XM_011522091 XP_011520393 XM_011522092 XP_011520394 NM_001142443 NP_001135915 NM_001142444 NP_001135916 NM_025083 NP_079359
|
Function |
Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis. {ECO:0000269|PubMed:16364915, ECO:0000269|PubMed:17533573, ECO:0000269|PubMed:18678652}.
|
Subcellular Location |
Cytoplasm, P-body {ECO:0000269|PubMed:16364915}. Note=Processing bodies (PB).
|
Tissue Specificity |
Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland. {ECO:0000269|PubMed:17533573}.
|
Top Pathways |
RNA degradation
|