EDC3

Gene Symbol EDC3
Entrez Gene 80153
Alt Symbol LSM16, YJDC, YJEFN2
Species Human
Gene Type protein-coding
Description enhancer of mRNA decapping 3
Other Description LSM16 homolog (EDC3, S. cerevisiae)|enhancer of mRNA decapping 3 homolog|enhancer of mRNA-decapping protein 3|hYjeF_N2|hYjeF_N2-15q23|yjeF N-terminal domain-containing protein 2|yjeF domain containing|yjeF domain-containing protein 1|yjeF_N2
Swissprots Q9H797 D3DW61 Q96F86 B3KPH0
Accessions EAW99316 EAW99317 EAW99318 EAW99319 Q96F86 AF193058 AAG22486 AK024781 BAB15001 AK056339 BAG51682 AK225099 AL133447 BC011534 AAH11534 BC021271 AAH21271 BM999594 CA440205 DA168050 DB007958 XM_011522091 XP_011520393 XM_011522092 XP_011520394 NM_001142443 NP_001135915 NM_001142444 NP_001135916 NM_025083 NP_079359
Function Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis. {ECO:0000269|PubMed:16364915, ECO:0000269|PubMed:17533573, ECO:0000269|PubMed:18678652}.
Subcellular Location Cytoplasm, P-body {ECO:0000269|PubMed:16364915}. Note=Processing bodies (PB).
Tissue Specificity Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland. {ECO:0000269|PubMed:17533573}.
Top Pathways RNA degradation

EDC3 (D2T7U) Rabbit mAb - 14495 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2T7U
Western blot analysis of extracts from various cell lines using EDC3 (D2T7U) Rabbit mAb.

EDC3 Antibody - 12469 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

Edc3 (D-6) - sc-365024 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Edc3 (D-6): sc-365024. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic and mRNA processing body (p-body) localization.

Edc3 (E-20) - sc-55080 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Edc3 (E-20): sc-55080. Western blot analysis of Edc3 expression in non-transfected: sc-110760 (A) and human Edc3 transfected: sc-111192 (B) 293 whole cell lysates.

Edc3 (F-9) - sc-271806 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Edc3 (F-9): sc-271806. Western blot analysis of Edc3 expression in non-transfected: sc-110760 (A) and human Edc3 transfected: sc-111192 (B) 293 whole cell lysates.

Edc3 (B-9) - sc-271732 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Edc3 (B-9): sc-271732. Western blot analysis of Edc3 expression in non-transfected: sc-110760 (A) and human Edc3 transfected: sc-111192 (B) 293 whole cell lysates.

Edc3 (G-16) - sc-55081 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Edc3 (G-16): sc-55081. Western blot analysis of Edc3 expression in non-transfected: sc-110760 (A) and human Edc3 transfected: sc-111192 (B) 293 whole cell lysates.

Edc3 (T-19) - sc-55083 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Edc3 (H-300) - sc-135013 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Edc3 (H-300): sc-135013. Western blot analysis of Edc3 expression in non-transfected 293: sc-110760 (A), human Edc3 transfected 293: sc-111192 (B) and 3T3-L1 (C) whole cell lysates.

Anti-EDC3 antibody - ab57780 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Overlay histogram showing HeLa cells stained with ab57780 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab57780, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-EDC3 antibody - ab168851 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EDC3 antibody (ab168851) at 0.1 µgLane 1 : 293T whole cell lysateLane 2 : HeLa whole cell lysateLane 3 : Jurkat whole cell lysateLane 4 : TCMK-1 whole cell lysateLane 5 : NIH3T3 whole cell lysateLysates/proteins at 50 µg per lane.developed using the ECL technique

Anti-EDC3 antibody - ab96190 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-EDC3 antibody (ab96190) at 1/3000 dilution + A431 whole cell lysate at 30 µg

Anti-EDC3 antibody - ab156380 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-EDC3 antibody (ab156380) at 1/100 dilution + 293 cell lysate at 35 µg

Anti-EDC3 Antibody (aa25-75) IHC-plus™ - LS-B11579 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-EDC3 Antibody (aa219-247, APC) - LS-C234857 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDC3 Antibody (phospho-Ser161) - LS-C209366 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EDC3 Antibody (aa219-247, AP) - LS-C234858 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDC3 Antibody (aa219-247, FITC) - LS-C234859 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDC3 Antibody (aa219-247, Biotin) - LS-C234860 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDC3 Antibody (aa219-247, PE) - LS-C234864 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDC3 Antibody (aa219-247, Azide-free, HRP) - LS-C249890 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDC3 Antibody (aa219-247) - LS-C321014 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EDC3 Antibody (clone 4E3-3A4) - LS-C308828 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4E3-3A4

Anti-EDC3 Antibody (aa1-509, Azide-free) - LS-C327275 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-EDC3 Antibody (aa175-224) - LS-C169755 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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