Gene Symbol | Grin3b |
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Entrez Gene | 170483 |
Alt Symbol | GluN3B, NR3B |
Species | Mouse |
Gene Type | protein-coding |
Description | glutamate receptor, ionotropic, NMDA3B |
Other Description | N-methyl-D-aspartate receptor subunit NR3B|NMDA receptor 4|NMDAR3B|glutamate [NMDA] receptor subunit 3B|glutamate receptor ionotropic, NMDA 3B|nr4 |
Swissprots | Q8VHV0 Q91ZU9 |
Accessions | EDL31619 Q91ZU9 AF373861 AAL40418 AF396649 AAL10018 AY062435 AAL38983 BC115747 AAI15748 BC152738 AAI52739 XM_006513287 XP_006513350 XM_006513288 XP_006513351 XM_006513289 XP_006513352 NM_130455 NP_569722 |
Function | NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:14602821}; Multi-pass membrane protein {ECO:0000269|PubMed:14602821}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000269|PubMed:14602821}. Note=Requires the presence of GRIN1 to be targeted at the plasma membrane. |
Tissue Specificity | Expressed in the facial nucleus and the ambiguus nucleus of the brainstem, pons, medulla, spinal cord and cerebellum. {ECO:0000269|PubMed:11717388, ECO:0000269|PubMed:12008020, ECO:0000269|PubMed:14602821}. |
Top Pathways | Glutamatergic synapse, Amphetamine addiction, Nicotine addiction, Cocaine addiction, Alcoholism |
NR3B (D-16) - sc-55727 from Santa Cruz Biotechnology
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NR3B (M-300) - sc-50474 from Santa Cruz Biotechnology
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Anti-GRIN3B / NR3B Antibody (aa916-930) - LS-C25799 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (aa903-933, AP) - LS-C235980 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (aa903-933, APC) - LS-C235981 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (aa903-933, Biotin) - LS-C235982 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (aa903-933, FITC) - LS-C235984 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (aa903-933, PE) - LS-C235985 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (aa903-933, Azide-free, HRP) - LS-C249137 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (aa903-933) - LS-C329602 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (aa1031-1042) - LS-C113030 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (aa904-933) - LS-C166680 from LifeSpan Bioscience
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NR3B, Polyclonal Antibody - MBS611857 from MyBioSource
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Anti-NR3B Antibody - 07-351 from EMD Millipore
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Anti-NR3B Antibody - 07-351 from Sigma-Aldrich
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Anti-GRIN3B / NR3B Antibody (APC) - LS-C518452 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (AP) - LS-C510295 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (Biotin) - LS-C528335 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (HRP) - LS-C548436 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody - LS-C496794 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (FITC) - LS-C538293 from LifeSpan Bioscience
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Anti-GRIN3B / NR3B Antibody (PE) - LS-C656461 from LifeSpan Bioscience
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