Gene Symbol | EML1 |
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Entrez Gene | 2009 |
Alt Symbol | ELP79, EMAP, EMAPL, HuEMAP |
Species | Human |
Gene Type | protein-coding |
Description | echinoderm microtubule associated protein like 1 |
Other Description | EMAP-1|echinoderm microtubule-associated protein-like 1|huEMAP-1 |
Swissprots | Q8WWL6 O00423 Q8N536 Q86U15 Q8N5C4 |
Accessions | CAD12600 EAW81679 EAW81680 EAW81681 O00423 AF035276 AK023861 AK126980 BAG54415 AK299812 BAH13136 AK307925 BC032541 AAH32541 BC033043 AAH33043 BX247979 CAD62313 BX420178 BX442035 DQ891556 ABM82482 DQ894743 ABM85669 U97018 AAB57824 XM_005267397 XP_005267454 XM_005267398 XP_005267455 XM_005267399 XP_005267456 XM_005267400 XP_005267457 XM_011536540 XP_011534842 XM_011536541 XP_011534843 XM_011536542 XP_011534844 NM_001008707 NP_001008707 NM_004434 NP_004425 |
Function | Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Detected in cytoplasmic punctae. Co-localizes with microtubules. Enriched in perinuclear regions during interphase and in the region of spindle microtubules during metaphase. Enriched at the midzone during telophase and cytokinesis. Detected at growth cones in neurons (By similarity). {ECO:0000250}. |
Tissue Specificity | Ubiquitous; expressed in most tissues with the exception of thymus and peripheral blood lymphocytes. {ECO:0000269|PubMed:10521658}. |
Human EML1 full length protein - ab116907 from Abcam
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Human EML1 full length protein - ab158354 from Abcam
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Human EML1 peptide - ab45435 from Abcam
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Human EML1 protein fragment - ab158355 from Abcam
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EML1 / EMAP Antibody Blocking Peptide - LS-E18578 from LifeSpan Bioscience
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Recombinant Human EML1 Protein - H00002009-P01 from Novus Biologicals
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Recombinant Human EML1 Protein - H00002009-Q01 from Novus Biologicals
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Recombinant Human EML1 Protein - H00002009-P02 from Novus Biologicals
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EMAL1-Antibody-Center-Blocking-Peptide - BP6733c from Abgent, a WuXi AppTec company
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EMAL1-Antibody-N-term-Blocking-Peptide - BP6733a from Abgent, a WuXi AppTec company
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EML1 Blocking Peptide - 33R-10195 from Fitzgerald
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EMAP1 / EML1 - H00002009-P01 from Acris Antibodies
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EMAP1 / EML1 - H00002009-P01-10 from Acris Antibodies
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EMAP1 / EML1 - H00002009-P01-25 from Acris Antibodies
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EMAP1 / EML1 - H00002009-P02 from Acris Antibodies
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EMAP1 / EML1 - H00002009-Q01-10 from Acris Antibodies
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EMAP1 / EML1 - H00002009-Q01-25 from Acris Antibodies
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EML1 fusion protein - ag3429 from Proteintech Group
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Recombinant Human EML1 - EML1-28291TH from Creative Biomart
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Recombinant Human Echinoderm microtubule-associated protein-like 1(EML1) ,partial - CSB-YP007642HU CSB-EP007642HU CSB-BP007642HU CSB-MP007642HU from Cusabio
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EML1 Recombinant Protein Antigen - NBP2-38601PEP from Novus Biologicals
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EML1 Peptide, Human - M34GP04909H from Creative Peptides
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Echinoderm microtubule-associated protein-like 1 (EML1), partial, Recombinant Protein - MBS1213190 from MyBioSource
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