Gene Symbol | EML1 |
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Entrez Gene | 2009 |
Alt Symbol | ELP79, EMAP, EMAPL, HuEMAP |
Species | Human |
Gene Type | protein-coding |
Description | echinoderm microtubule associated protein like 1 |
Other Description | EMAP-1|echinoderm microtubule-associated protein-like 1|huEMAP-1 |
Swissprots | Q8WWL6 O00423 Q8N536 Q86U15 Q8N5C4 |
Accessions | CAD12600 EAW81679 EAW81680 EAW81681 O00423 AF035276 AK023861 AK126980 BAG54415 AK299812 BAH13136 AK307925 BC032541 AAH32541 BC033043 AAH33043 BX247979 CAD62313 BX420178 BX442035 DQ891556 ABM82482 DQ894743 ABM85669 U97018 AAB57824 XM_005267397 XP_005267454 XM_005267398 XP_005267455 XM_005267399 XP_005267456 XM_005267400 XP_005267457 XM_011536540 XP_011534842 XM_011536541 XP_011534843 XM_011536542 XP_011534844 NM_001008707 NP_001008707 NM_004434 NP_004425 |
Function | Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Detected in cytoplasmic punctae. Co-localizes with microtubules. Enriched in perinuclear regions during interphase and in the region of spindle microtubules during metaphase. Enriched at the midzone during telophase and cytokinesis. Detected at growth cones in neurons (By similarity). {ECO:0000250}. |
Tissue Specificity | Ubiquitous; expressed in most tissues with the exception of thymus and peripheral blood lymphocytes. {ECO:0000269|PubMed:10521658}. |
EML1 (B-3) - sc-390841 from Santa Cruz Biotechnology
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EML1 (H-61) - sc-292183 from Santa Cruz Biotechnology
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EML1 (K-16) - sc-47879 from Santa Cruz Biotechnology
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EML1 (C-13) - sc-47878 from Santa Cruz Biotechnology
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EML1 (N-16) - sc-47881 from Santa Cruz Biotechnology
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Anti-EML1 antibody - ab97342 from Abcam
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Anti-EML1 antibody - C-terminal - ab153703 from Abcam
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Anti-EML1 / EMAP Antibody (aa753-815) - LS-C185352 from LifeSpan Bioscience
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Anti-EML1 / EMAP Antibody (clone 5G3) - LS-C197131 from LifeSpan Bioscience
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Anti-EML1 / EMAP Antibody (C-Terminus) - LS-C81665 from LifeSpan Bioscience
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EML1 Antibody - NBP1-30956 from Novus Biologicals
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EML1 Antibody - NBP1-56595 from Novus Biologicals
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EML1 Antibody - NBP2-38601 from Novus Biologicals
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EML1 Antibody - NBP2-16327 from Novus Biologicals
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EML1 Antibody (5G3) - H00002009-M01A from Novus Biologicals
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Anti-EML1 antibody produced in rabbit - SAB2701166 from Sigma-Aldrich
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Monoclonal Anti-EML1 antibody produced in mouse - WH0002009M1 from Sigma-Aldrich
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Anti-EML1 antibody produced in rabbit - SAB2100680 from Sigma-Aldrich
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Anti-EML1 (C-terminal) antibody produced in rabbit - SAB2700739 from Sigma-Aldrich
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Anti-EML1 (C-terminal) antibody produced in rabbit - SAB2701167 from Sigma-Aldrich
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EML1 antibody - C-terminal region (ARP51803_P050) - ARP51803_P050 from Aviva Systems Biology
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EML1-Antibody-monoclonal-M01 - AT1900a from Abgent, a WuXi AppTec company
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EML1 antibody [C2C3], C-term - GTX114382 from GeneTex
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EML1 antibody [C3], C-term - GTX100252 from GeneTex
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EML1 antibody [N1N3] - GTX114381 from GeneTex
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