| Gene Symbol |
DLAT
|
| Entrez Gene |
1737
|
| Alt Symbol |
DLTA, PDC-E2, PDCE2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dihydrolipoamide S-acetyltransferase
|
| Other Description |
70 kDa mitochondrial autoantigen of primary biliary cirrhosis|E2 component of pyruvate dehydrogenase complex|M2 antigen complex 70 kDa subunit|PBC|dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex|dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial|dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial|pyruvate dehydrogenase complex component E2
|
| Swissprots |
Q53EP3 P10515 Q16783
|
| Accessions |
ACA05975 EAW67174 EAW67175 P10515 AF317200 AAG31658 AK057299 BAG51900 AK223596 BAD97316 AK296274 BAG58983 AK297103 BAG59614 AK299562 BAG61505 AK303930 BAG64858 AL832703 AW188637 BC039084 AAH39084 DB551427 DQ892447 ABM83373 DQ895658 ABM86584 X13822 CAA32052 Y00978 CAA68787 XM_011542647 XP_011540949 NM_001931 NP_001922
|
| Function |
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
|
| Subcellular Location |
Mitochondrion matrix.
|
| Top Pathways |
Glycolysis / Gluconeogenesis, Citrate cycle (TCA cycle), Pyruvate metabolism, Carbon metabolism
|
![Western Blot: Pyruvate Dehydrogenase E2 Overexpression Lysate (Adult Normal) [NBL1-09906] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Pyruvate Dehydrogenase E2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/8600_Pyruvate%2520Dehydrogenase%2520E2%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-09906-img0002.jpg)