Gene Symbol | DLAT |
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Entrez Gene | 1737 |
Alt Symbol | DLTA, PDC-E2, PDCE2 |
Species | Human |
Gene Type | protein-coding |
Description | dihydrolipoamide S-acetyltransferase |
Other Description | 70 kDa mitochondrial autoantigen of primary biliary cirrhosis|E2 component of pyruvate dehydrogenase complex|M2 antigen complex 70 kDa subunit|PBC|dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex|dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial|dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial|pyruvate dehydrogenase complex component E2 |
Swissprots | Q53EP3 P10515 Q16783 |
Accessions | ACA05975 EAW67174 EAW67175 P10515 AF317200 AAG31658 AK057299 BAG51900 AK223596 BAD97316 AK296274 BAG58983 AK297103 BAG59614 AK299562 BAG61505 AK303930 BAG64858 AL832703 AW188637 BC039084 AAH39084 DB551427 DQ892447 ABM83373 DQ895658 ABM86584 X13822 CAA32052 Y00978 CAA68787 XM_011542647 XP_011540949 NM_001931 NP_001922 |
Function | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. |
Subcellular Location | Mitochondrion matrix. |
Top Pathways | Glycolysis / Gluconeogenesis, Citrate cycle (TCA cycle), Pyruvate metabolism, Carbon metabolism |
DLAT (4A4-B6-C10) Mouse mAb - 12362 from Cell Signaling Technology
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PDC-E2 (A-9) - sc-365276 from Santa Cruz Biotechnology
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PDC-E2 (C-9) - sc-271352 from Santa Cruz Biotechnology
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PDC-E2 (H-160) - sc-32925 from Santa Cruz Biotechnology
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PDC-E2 (B-2) - sc-271534 from Santa Cruz Biotechnology
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PDC-E2 (C-1) - sc-166899 from Santa Cruz Biotechnology
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PDC-E2 (N-20) - sc-16890 from Santa Cruz Biotechnology
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PDC-E2 (C-19) - sc-16892 from Santa Cruz Biotechnology
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Anti-Pyruvate Dehydrogenase E2 antibody - ab88884 from Abcam
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Anti-Pyruvate Dehydrogenase E2 antibody - ab103948 from Abcam
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Anti-Pyruvate Dehydrogenase E2 antibody - ab126224 from Abcam
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Anti-Pyruvate Dehydrogenase E2 antibody [4A4-B6-C10] - ab131200 from Abcam
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Anti-Pyruvate Dehydrogenase E2 antibody [EPR12455(B)] - ab172617 from Abcam
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Anti-DLAT / PDC-E2 Antibody - LS-C310138 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody (aa587-617) - LS-C320853 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody - LS-C334616 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody (aa587-617, AP) - LS-C222110 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody (aa587-617, APC) - LS-C222111 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody (aa61-110) - LS-C31961 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody (aa587-617, Biotin) - LS-C222112 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody (aa540-589) - LS-C80476 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody (aa587-617, FITC) - LS-C222113 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody (aa587-617, Azide-free, HRP) - LS-C222115 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody - LS-C178284 from LifeSpan Bioscience
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Anti-DLAT / PDC-E2 Antibody (aa587-617, PE) - LS-C222116 from LifeSpan Bioscience
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