Gene Symbol | CDC42BPG |
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Entrez Gene | 55561 |
Alt Symbol | DMPK2, HSMDPKIN, KAPPA-200, MRCKG, MRCKgamma |
Species | Human |
Gene Type | protein-coding |
Description | CDC42 binding protein kinase gamma (DMPK-like) |
Other Description | CDC42-binding protein kinase gamma|DMPK-like gamma|MRCK gamma|myotonic dystrophy kinase-related CDC42-binding kinase gamma|myotonic dystrophy protein kinase like protein|myotonic dystrophy protein kinase-like alpha|myotonic dystrophy protein kinase-like gamma|serine/threonine-protein kinase MRCK gamma |
Swissprots | O00565 Q6DT37 |
Accessions | CAF05454 EAW74316 Q6DT37 AY648038 AAT67172 BI793270 Y12337 CAA73006 XM_011545155 XP_011543457 XM_011545156 XP_011543458 XM_011545157 XP_011543459 XM_011545158 XP_011543460 XM_011545159 XP_011543461 XM_011545160 XP_011543462 XM_011545161 XP_011543463 XR_949988 XR_949989 NM_017525 NP_059995 |
Function | May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity). {ECO:0000250|UniProtKB:Q5VT25}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15194684}. Note=Concentrates at the leading edge of cells. |
Tissue Specificity | Expressed in heart and skeletal muscle. {ECO:0000269|PubMed:15194684}. |
MRCKγ (P-20) - sc-324138 from Santa Cruz Biotechnology
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MRCKγ (C-20) - sc-324140 from Santa Cruz Biotechnology
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Anti-CDC42BPG antibody - ab76669 from Abcam
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Anti-CDC42BPG Antibody (clone 2C3) - LS-C139340 from LifeSpan Bioscience
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CDC42BPG Antibody - NBP1-84072 from Novus Biologicals
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CDC42BPG Antibody - NBP2-38938 from Novus Biologicals
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CDC42BPG Antibody (2C3) - H00055561-M01 from Novus Biologicals
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Monoclonal Anti-CDC42BPG antibody produced in mouse - SAB1403292 from Sigma-Aldrich
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Anti-CDC42BPG antibody produced in rabbit - HPA027382 from Sigma-Aldrich
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MRCK alpha antibody - 70R-12679 from Fitzgerald
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CDC42BPG antibody - H00055561-A01 from Acris Antibodies
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CDC42BPG antibody - H00055561-M01 from Acris Antibodies
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Anti-CDC42BPG (aa 1423-1528) polyclonal antibody - DPAB-DC2415 from Creative Diagnostics
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Anti-CDC42 binding protein kinase gamma (DMPK-like) - 08A055561 from MP Biomedicals
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CDC42BPG Antibody - H00055561-A01 from Novus Biologicals
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MRCKG Antibody - DF2413 from Affinity Biosciences
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MRCKγ (2C3) - sc-517148 from Santa Cruz Biotechnology
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Anti-CDC42BPG antibody produced in rabbit - HPA061836 from Sigma-Aldrich
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Recombinant Anti-Human CDC42BPG Antibody - MOB-2594z from Creative Biolabs
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Recombinant Anti-Human CDC42BPG Antibody scFv Fragment - MOB-2594z-S(P) from Creative Biolabs
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Recombinant Anti-Human CDC42BPG Antibody Fab Fragment - MOB-2594z-F(E) from Creative Biolabs
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MRCKG Antibody - 44745 from Signalway Antibody
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MRCKG antibody - orb335223 from Biorbyt
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Mouse anti-Human CDC42BPG monoclonal antibody, clone 3D4 - CABT-B9921 from Creative Diagnostics
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