| Gene Symbol |
CDC42BPG
|
| Entrez Gene |
55561
|
| Alt Symbol |
DMPK2, HSMDPKIN, KAPPA-200, MRCKG, MRCKgamma
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CDC42 binding protein kinase gamma (DMPK-like)
|
| Other Description |
CDC42-binding protein kinase gamma|DMPK-like gamma|MRCK gamma|myotonic dystrophy kinase-related CDC42-binding kinase gamma|myotonic dystrophy protein kinase like protein|myotonic dystrophy protein kinase-like alpha|myotonic dystrophy protein kinase-like gamma|serine/threonine-protein kinase MRCK gamma
|
| Swissprots |
O00565 Q6DT37
|
| Accessions |
CAF05454 EAW74316 Q6DT37 AY648038 AAT67172 BI793270 Y12337 CAA73006 XM_011545155 XP_011543457 XM_011545156 XP_011543458 XM_011545157 XP_011543459 XM_011545158 XP_011543460 XM_011545159 XP_011543461 XM_011545160 XP_011543462 XM_011545161 XP_011543463 XR_949988 XR_949989 NM_017525 NP_059995
|
| Function |
May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity). {ECO:0000250|UniProtKB:Q5VT25}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15194684}. Note=Concentrates at the leading edge of cells.
|
| Tissue Specificity |
Expressed in heart and skeletal muscle. {ECO:0000269|PubMed:15194684}.
|
![Western Blot: CDC42BPG Overexpression Lysate (Adult Normal) [NBP2-06969] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CDC42BPG.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5785_CDC42BPG%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06969-img0001.jpg)