Gene Symbol | CNGA1 |
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Entrez Gene | 1259 |
Alt Symbol | CNCG, CNCG1, CNG-1, CNG1, RCNC1, RCNCa, RCNCalpha, RP49 |
Species | Human |
Gene Type | protein-coding |
Description | cyclic nucleotide gated channel alpha 1 |
Other Description | CNG channel alpha-1|cGMP-gated cation channel alpha-1|cyclic nucleotide-gated cation channel 1|cyclic nucleotide-gated channel alpha-1|cyclic nucleotide-gated channel, photoreceptor|interleukin-1 homologue|rod photoreceptor cGMP-gated channel subunit alpha |
Swissprots | Q4W5E3 Q16485 Q16279 J3KPZ2 A8K7K6 P29973 |
Accessions | AAD14206 AAY40919 EAW93048 EAW93049 P29973 AK292021 BAF84710 BC140399 AAI40400 M84741 AAA52010 S42457 AAB22778 W89170 W93472 X64802 CAA46027 XM_005248049 XP_005248106 XM_011513623 XP_011511925 NM_000087 NP_000078 NM_001142564 NP_001136036 |
Function | Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Rod cells in the retina. |
Top Pathways | Phototransduction, cGMP-PKG signaling pathway, cAMP signaling pathway |
CNG-1 (C-20) - sc-13693 from Santa Cruz Biotechnology
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CNG-1 (N-18) - sc-13690 from Santa Cruz Biotechnology
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CNG-1 (H-151) - sc-366043 from Santa Cruz Biotechnology
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CNG-3 (E-15) - sc-21927 from Santa Cruz Biotechnology
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Anti-CNG1 antibody - ab136123 from Abcam
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Anti-CNG1 antibody [CNC 9C1] - ab32676 from Abcam
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Anti-RP49 / CNG1 Antibody (N-Terminus) - LS-C14502 from LifeSpan Bioscience
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Anti-RP49 / CNG1 Antibody (C-Terminus) - LS-C14503 from LifeSpan Bioscience
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Anti-RP49 / CNG1 Antibody (C-Terminus) - LS-C14504 from LifeSpan Bioscience
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Anti-RP49 / CNG1 Antibody (N-Terminus) - LS-C14729 from LifeSpan Bioscience
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Anti-RP49 / CNG1 Antibody (aa401-450) - LS-C291307 from LifeSpan Bioscience
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Anti-RP49 / CNG1 Antibody (aa384-433) - LS-C291814 from LifeSpan Bioscience
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CNG1 Antibody (CNC 9C1) - NB100-74389 from Novus Biologicals
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CNG1 Antibody - NBP1-46271 from Novus Biologicals
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Anti-CNGA1 antibody produced in rabbit - SAB4301127 from Sigma-Aldrich
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CNGA1/3 Antibody (OASE00237) - OASE00237 from Aviva Systems Biology
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CNGA1 Antibody (OAAF03481) - OAAF03481 from Aviva Systems Biology
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CNGA1 Antibody (OAAF06241) - OAAF06241 from Aviva Systems Biology
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CNGA1 antibody (ATTO-680) - orb149636 from Biorbyt
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Anti -CNG1 (Cyclic Nucleotide-Gated Channels 1) - C5999-15 from USBiological Life Science
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Anti -CNG1 (Cyclic Nucleotide-Gated Channels 1) - C5999-20 from USBiological Life Science
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CNGA1 antibody (PE/ATTO-594) - orb149643 from Biorbyt
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CNGA1 Antibody - abx014349 from Abbexa
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CNGA1 antibody - H00001259-B01P from Acris Antibodies
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CNGA1-Specific antibody - 19682-1-AP from Proteintech Group
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