Gene Symbol | KCTD12 |
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Entrez Gene | 115207 |
Alt Symbol | C13orf2, PFET1, PFETIN |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel tetramerization domain containing 12 |
Other Description | BTB/POZ domain-containing protein KCTD12|potassium channel tetramerisation domain containing 12|predominantly fetal expressed T1 domain |
Swissprots | Q96CX2 |
Accessions | EAW80558 Q96CX2 AF052169 AF359381 AAQ15187 AK057635 AK128363 BAG54666 BC013764 AAH13764 BU742274 DB153209 NM_138444 NP_612453 |
Function | Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity). {ECO:0000250}. |
Subcellular Location | Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. |
Tissue Specificity | Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung. {ECO:0000269|PubMed:15357420}. |
KCTD12 Antibody Blocking Peptide - LS-E10037 from LifeSpan Bioscience
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KCTD12-Antibody-Center-Blocking-Peptide - BP9273c from Abgent, a WuXi AppTec company
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KCTD12 fusion protein - Ag5716 from Proteintech Group
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Recombinant Human KCTD12, His-tagged - KCTD12-291H from Creative Biomart
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Recombinant Human BTB/POZ domain-containing protein KCTD12(KCTD12) - CSB-YP842652HU CSB-EP842652HU CSB-BP842652HU CSB-MP842652HU from Cusabio
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KCTD12 Peptide, Human - M34GP08016H from Creative Peptides
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BTB/POZ domain-containing protein KCTD12 (KCTD12), Recombinant Protein - MBS1461201 from MyBioSource
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