Gene Symbol |
TUSC2
|
Entrez Gene |
11334
|
Alt Symbol |
C3orf11, FUS1, PAP, PDAP2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
tumor suppressor candidate 2
|
Other Description |
PDGFA associated protein 2|PDGFA-associated protein 2|fus-1 protein|fusion 1 protein
|
Swissprots |
O75896 B2R4Y9
|
Accessions |
EAW65095 EAW65096 EAW65097 O75896 AF055479 AAC35497 AK124058 AK311998 BAG34936 BC023976 AAH23976 CA392689 HQ448135 ADQ32616 NM_007275 NP_009206
|
Function |
May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
|
Tissue Specificity |
Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.
|